Cell surface markers

Question 1

4 T cell receptors for all T cells

Answer 1

TCR - binds MHC
CD3 - associated with TCR signal transduction
CD 28 - binds APC B7
CCR5 = HIV co-receptor

Question 2

CD 4 markers

Answer 2

CD4

CD 40 L

Question 3

CD8 markers

Answer 3

CD 8

CCD5 coreceptor for HIV

Question 4

Regulatory T cell markers

Answer 4

CD 4
CD 25
FOXP3

Question 5

B cell markers

Answer 5

Ig - binds antigen
CD 19, 20
CD 21 binds EBV
CD 40
MHC 2, B7

Question 6

Macrophage markers

Answer 6

CD 14 - receptor for PAMPs
CD 40
CCR5
MHC 2, B7
Fc + C3b receptors - enhanced phagocytosis

Question 7

NK cells receptors

Answer 7

CD 56 = unique

CD 16 = binds Fc of bound IgG

Question 8

Hematopoietic stem cell marker

Answer 8

CD 34