Auto Abs Flashcards

1
Q

MG

A

Anti ACh R Ab (T2 HST)

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2
Q

Goodpasture

A

Ab vs T4 collagen (T2 HST)

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3
Q

SLE

A
Anti cardiolipin
Lupus anticoag
Anti dsDNA
Anti-Smith = vs snRNPs which splice pre-mRNA before leaving the nucleus (remove introns)
ANA - sensitive
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4
Q

CREST = limited scleroderma

A

Anti-centromere

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5
Q

Pemphigus vulgaris

A

Anti desmosome (T2 HST)

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6
Q

T1 DM

A

Anti glutamic acid decarboxylase

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7
Q

Bullous pemphigoid

A

Anti-hemidesmisome

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8
Q

Drug induced SLE

A

Anti histone

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9
Q

Polymyositis, dermatomyositis

A

Anti Jo 1
Anti SRP
Anti Mi 2

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10
Q

Hashimoto

A

Anti thyroglobulin

Anti microsomal

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11
Q

1ary biliary cirrhosis

A

Anti mito

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12
Q

Pernicious anemia

A

Ab vs parietal cell

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13
Q

1ary membranous nephropathy

A

Ab vs phospholipase A2 receptor

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14
Q

Diffuse scleroderma

A

Anti Scl 70 = anti DNA topo 1

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15
Q

AI hepatitis type 1

A

Anti smooth muscle

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16
Q

Sjogren syndrome

A

Anti SSA, SSB

17
Q

Graves

A

Ab vs TSH R

18
Q

Mixed CT disease

A

Anti UP RNP - helps with mRNA splicing

19
Q

Lambert Eaton

A

Ab vs voltage gated Ca channels

20
Q

Celiac

A

IgA vs endomysial

IgA vs tissue transglutaminase

21
Q

Microscopic polyangitis + eosinophilic granulomatosis w/ polyangitits

A

Ab vs pANCA (MPO ANCA)

22
Q

Granulomatosis w/ polyangiitis (Wegner)

A

Ab vs cANCA (PR3 ANCA)

23
Q

RA

A

IgM vs IgG Fc region = RF

Anti CCP = specific