Auto Abs

Question 1

MG

Answer 1

Anti ACh R Ab (T2 HST)

Question 2

Goodpasture

Answer 2

Ab vs T4 collagen (T2 HST)

Question 3

SLE

Answer 3

Anti cardiolipin
Lupus anticoag
Anti dsDNA
Anti-Smith = vs snRNPs which splice pre-mRNA before leaving the nucleus (remove introns)
ANA - sensitive

Question 4

CREST = limited scleroderma

Answer 4

Anti-centromere

Question 5

Pemphigus vulgaris

Answer 5

Anti desmosome (T2 HST)

Question 6

T1 DM

Answer 6

Anti glutamic acid decarboxylase

Question 7

Bullous pemphigoid

Answer 7

Anti-hemidesmisome

Question 8

Drug induced SLE

Answer 8

Anti histone

Question 9

Polymyositis, dermatomyositis

Answer 9

Anti Jo 1
Anti SRP
Anti Mi 2

Question 10

Hashimoto

Answer 10

Anti thyroglobulin

Anti microsomal

Question 11

1ary biliary cirrhosis

Answer 11

Anti mito

Question 12

Pernicious anemia

Answer 12

Ab vs parietal cell

Question 13

1ary membranous nephropathy

Answer 13

Ab vs phospholipase A2 receptor

Question 14

Diffuse scleroderma

Answer 14

Anti Scl 70 = anti DNA topo 1

Question 15

AI hepatitis type 1

Answer 15

Anti smooth muscle

Question 16

Sjogren syndrome

Answer 16

Anti SSA, SSB

Question 17

Graves

Answer 17

Ab vs TSH R

Question 18

Mixed CT disease

Answer 18

Anti UP RNP - helps with mRNA splicing

Question 19

Lambert Eaton

Answer 19

Ab vs voltage gated Ca channels

Question 20

Celiac

Answer 20

IgA vs endomysial

IgA vs tissue transglutaminase

Question 21

Microscopic polyangitis + eosinophilic granulomatosis w/ polyangitits

Answer 21

Ab vs pANCA (MPO ANCA)

Question 22

Granulomatosis w/ polyangiitis (Wegner)

Answer 22

Ab vs cANCA (PR3 ANCA)

Question 23

RA

Answer 23

IgM vs IgG Fc region = RF

Anti CCP = specific