cell membrane Flashcards

1
Q

cell membrane function

A

generation of electrical signals
embedded proteins for sensing change
protection
have attachment sites as adhesion points

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2
Q

lipid bilayer contain…

A

proteins embedded/attached via non-covalent interaction

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3
Q

phospholipids consists of

A

amphiphilic molecule with non-polar hydrophobic tail and polar hydrophilic heads

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4
Q

lipid function in membrane

A

self organising and is around 50% of membrane mass

for spheres to make sealed compartment = enclosed cell

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5
Q

major phospholipids names

A
glycolipid
phosphatidylemanolamine
phosphatidylserine(-ve charge)
phosphatidylcholine
sphingomyelin
sphingosime - used to build sphingomyelin
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6
Q

artificial liposomes

A

phospholipid bilayer in aq solution

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7
Q

cholesterol

A

polar head and non-polar tail

plants have sterol compound

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8
Q

fluidity of membrane when temp decreases

A

decrease in kinetic energy
phospholipids pack together
forming a crystalline state

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9
Q

fluidity of cholesterol when temp decreases

A

increase spacing between the hydrocarbons

increase in fluidity

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10
Q

flexion

A

movement of HC tails

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11
Q

fluidity of cholesterol when temp increases

A

pulls HC tails together

decreases fluidity - stabilise

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12
Q

fluidity of membrane when temp increases

A

kinetic increases
increase movement therefore packed less tightly
increase fluidity

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13
Q

lateral

A

movement of phospholipid within planes

rapidly

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14
Q

flip-flopping

A

movement of phospholipids between planes

more rare

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15
Q

Result of Cis double bonding

A

more difficult to pack
HC are shorter and more spread out
bilayer becomes thinner

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16
Q

lipid raft

A

more stable and move as a big unit
keep proteins associated together
contains more cholesterol and sphingolipids = move laterally

17
Q

experiment of movement of proteins in membrane

A

human + mouse cell = hybrid

proteins monitored using antibodies and fluorescent dye

18
Q

result of experiment of proteins

A

At 0 - dye is at either half of the cell
At 40 mins - dye is distributed
therefore protein is mobile in the membrane