Cell membrane Flashcards
first account of semi-permeability of cell membrane
- when
- who
- first discovery re composition (2)
- 1890s
- Ernst Overton
- Membrane has lipid nature w Cholesterol and Lecithins
behaviour of lipid monolayer
- when
- who
- discovery (2)
- 1917
- Irving Langmuir
- Hydrophilic Heads & Hydrophobic Tails
Proposal of Biomolecular Lipid Leaflet Model
- when
- who
- 1925
- Gorter and Grendel
Development of Protein-Lipid Sandwich Model
- when
- who
- discovery (1)
- 1935
- Davson and Danielli
- membrane contains PROTEIN SHEETS
Proposal of Trilayer Membrane
- when
- who
- 1967
- Robertson
Whose (3 inventors) models (2 models) cannot explain how globular proteins can form thin protein sheets and allow substance transport
Davson-Davielli
and
Rovertson
What happened in 1966?
- who
- discovery
- Mueller and Rudin
- bilayer with fluidity and self-healing
What happened in 1972?
- who
- model
- Singer and Nicolson
- Fluid Mosaic Membrane
3 FACTORS that affect fluidity
- Temperature (direct)
- Cholesterol (indirect)
- Fatty Acid (indirect w SF; direct with UF)
2 TYPES of fatty acids
- Saturated
- Unsaturated
Other term for hydrophobic tails
HYDROCARBON TAILS
What type of fatty acids a) has a bent tail, b) what do u call that tail c) reason for such
a. unsaturated
b. kink
3. presence of double bonds
How many parts in cell membrane
13
Glycoprotein (may carbs na nakadikit sa taas)
Cholesterol is found in between tails
3 main components of the cell membrane
- lipids
- proteins
- carbohydrates
2 examples of carbohydrates found in cell membrane
glycolipids
glycoproteins
2 examples of lipids found in cell membrane
phospholipids
sterol
Two main features in FLUID MOSAIC MEMBRANE
fluidity and mosaicity
3 types of proteins
Integral Proteins: Act as channels, receptors, or transporters across the membrane.
Peripheral Proteins: Provide support, cell shape, and signaling near the membrane.
Lipid-Anchored Proteins: Involved in cell signaling and can localize to specific membrane regions.
How is semi-permeability shown in cell membrane
phospholipid layer
integral proteins
MOLECULES THAT
- cannot pass
- can pass
CANNOT: large,polar,charged
CAN: small, nonpolar, uncharged
Function of GLYCOCALYX
Antigenic Function
Where are carbs attached
proteins and lipids