Cell membrane Flashcards

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1
Q

first account of semi-permeability of cell membrane

  • when
  • who
  • first discovery re composition (2)
A
  • 1890s
  • Ernst Overton
  • Membrane has lipid nature w Cholesterol and Lecithins
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2
Q

behaviour of lipid monolayer

  • when
  • who
  • discovery (2)
A
  • 1917
  • Irving Langmuir
  • Hydrophilic Heads & Hydrophobic Tails
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3
Q

Proposal of Biomolecular Lipid Leaflet Model

  • when
  • who
A
  • 1925
  • Gorter and Grendel
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4
Q

Development of Protein-Lipid Sandwich Model

  • when
  • who
  • discovery (1)
A
  • 1935
  • Davson and Danielli
  • membrane contains PROTEIN SHEETS
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5
Q

Proposal of Trilayer Membrane

  • when
  • who
A
  • 1967
  • Robertson
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6
Q

Whose (3 inventors) models (2 models) cannot explain how globular proteins can form thin protein sheets and allow substance transport

A

Davson-Davielli

and
Rovertson

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7
Q

What happened in 1966?

  • who
  • discovery
A
  • Mueller and Rudin
  • bilayer with fluidity and self-healing
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8
Q

What happened in 1972?

  • who
  • model
A
  • Singer and Nicolson
  • Fluid Mosaic Membrane
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9
Q

3 FACTORS that affect fluidity

A
  1. Temperature (direct)
  2. Cholesterol (indirect)
  3. Fatty Acid (indirect w SF; direct with UF)
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10
Q

2 TYPES of fatty acids

A
  1. Saturated
  2. Unsaturated
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11
Q

Other term for hydrophobic tails

A

HYDROCARBON TAILS

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12
Q

What type of fatty acids a) has a bent tail, b) what do u call that tail c) reason for such

A

a. unsaturated
b. kink
3. presence of double bonds

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13
Q

How many parts in cell membrane

A

13

Glycoprotein (may carbs na nakadikit sa taas)
Cholesterol is found in between tails

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14
Q

3 main components of the cell membrane

A
  1. lipids
  2. proteins
  3. carbohydrates
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15
Q

2 examples of carbohydrates found in cell membrane

A

glycolipids

glycoproteins

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16
Q

2 examples of lipids found in cell membrane

A

phospholipids

sterol

17
Q

Two main features in FLUID MOSAIC MEMBRANE

A

fluidity and mosaicity

18
Q

3 types of proteins

A

Integral Proteins: Act as channels, receptors, or transporters across the membrane.

Peripheral Proteins: Provide support, cell shape, and signaling near the membrane.

Lipid-Anchored Proteins: Involved in cell signaling and can localize to specific membrane regions.

19
Q

How is semi-permeability shown in cell membrane

A

phospholipid layer

integral proteins

20
Q

MOLECULES THAT

  • cannot pass
  • can pass
A

CANNOT: large,polar,charged

CAN: small, nonpolar, uncharged

21
Q

Function of GLYCOCALYX

A

Antigenic Function

22
Q

Where are carbs attached

A

proteins and lipids