Cell Function 1 Flashcards
Principles of homeostasis
stable functional state, when faced with environmental changes (internal = endogenous, external = exogenous)
Feedback control systems require
sensor
integrator
effector
When will a feedback loop close?
The loop closes when the sensor detects normal levels and reports to integrator which reports to effector
Costs energy to operate
What is a negative feedback loop?
Most common
Biochemical entity acts on an earlier event to prevent more of itself from being formed
Wants to stay near set point
Examples of negative feedback loops?
Control of arterial blood pressure
Control of blood glucose concentration
Interconversion of metabolites in a series of enzymatic reactions
What is a positive feedback loop?
Rare
Accelerates/amplifys change
Promotes instability
Wants to deviate from set point
Examples of positive feedback loops?
Ovulation
Transmission of an action potential in excitable cells