Cell Division, Diversity and Organisation - Chromosomes and Cell Cycle Flashcards

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1
Q

how is each chromatid held together

A

by the centromere

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2
Q

describe chromosomes during interphase

A

each DNA molecule makes a copy of itself
chromosomes are then composed of two identical chromatids

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3
Q

what are homologous pairs

A

one of each pair come from the father and from the mother (same genes, but possibly different alleles)

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4
Q

what are autosomes

A

the remaining chromosomes that aren’t sex chromosomes

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5
Q

how many sets of chromosomes to gametes have

A

one (haploid)

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6
Q

how many sets of chromosomes do body cells have

A

two (diploid)

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7
Q

what are the phases of the cell cycle

A

interphase (G1, S, G2)
prophase
metaphase
anaphase
telophase

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8
Q

describe interphase

A
  • DNA is uncoiled and not visible during interphase
  • DNA replication occurs (S) and DNA is checked for errors
  • centrioles replicate (animal cells only) (G1 and G2)
  • cell increases in size (more cytoplasm)
  • new organelles produced
  • cell is very active and large amounts of ATP required
  • protein synthesis occurs
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9
Q

describe prophase

A
  • chromosomes become visible as they shorten and thicken
  • centrioles move to opposite ends (poles) of the cell
  • microtubules develop from pole to pole forming spindle fibres
  • nucleolus disappears (forms part of several chromosomes)
  • nuclear envelope breaks down
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10
Q

describe metaphase

A
  • centrioles reach the two poles
  • chromosomes line up at the equator of the cell
  • the spindle fibres attach to the centromere on each chromosome and pull the chromosomes to arrange them along the equator of the cell
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11
Q

describe anaphase

A
  • the centromeres divide
  • the spindle fibres contract and shorten, pulling the chromatids apart, centromere leading, towards opposite ends of the cell
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12
Q

describe telophase

A
  • the chromatids have now reached the poles and can be regarded as distinct chromosomes
  • the nuclear envelope reforms around each group of chromosomes
  • the nucleolus reappears
  • the chromosomes uncoil to form chromatin
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13
Q

describe cytokinesis in an animal cell

A

cell division involves furrowing and cleavage of the cytoplasm

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14
Q

where does cytokinesis begin in an animal cell

A

the edge of the cell

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15
Q

describe cytokinesis in a plant cell

A

cell division involves formation of a cell plate

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16
Q

where does cytokinesis begin in a plant cell

A

the middle of the cell

17
Q

what are the four functions of mitosis

A
  • asexual reproduction
  • growth in multicellular organisms
  • repair of tissues (same marking point)
  • replacement of cells (same marking point)
18
Q

why is it important that gametes contain the haploid number of chromosomes

A
  • restores diploid number
  • prevents doubling of chromosomes
19
Q

What are checkpoints of the cell cycle

A

Monitor whether each stage of the cell cycle has been completed before the cell can proceed to the next step

20
Q

What are the purposes of checkpoints

A
  • prevent uncontrolled cell division leading to tumours
  • detect and repair damage to DNA
  • ensure cell cycle is not reversed
  • ensure DNA is only copied once during each cell cycle
21
Q

What are the three checkpoints of the cell cycle

A
  • G1 checkpoint
  • G2 checkpoint
  • spindle assembly checkpoint
22
Q

What does the G1 checkpoint check for

A
  • cell size
  • nutrients
  • growth factors
  • DNA damage
23
Q

What does the G2 checkpoint check for

A
  • DNA replication (no DNA damaged)
  • cell size
24
Q

What does the spindle assembly checkpoint check for

A

Chromosome attached to spindle fibre

25
Q

What does the cell enter if a problem is found or DNA is damaged

A

G0 phase

26
Q

What is G0 or resting phase

A

Cells leave the cell cycle permanently or temporarily

27
Q

What happens during resting phase/why does it happen

A
  • cell differentiation, once specialised some cells won’t undergo mitosis again
  • if DNA is damaged (majority of cells have limited number of times they divide)
  • lymphocytes, can start dividing again and re enter cell cycle is
28
Q

What happens if the damage can’t be repaired

A

Apoptosis

29
Q

Where does mitosis take place in animal cells

A

Many cells are capable of mitosis

30
Q

Where does mitosis take place in plant cells

A

Only special regions called meristems can undergo mitosis

31
Q

Why can only meristems perform mitosis

A

Meristem cells have very thin cell walls. Older cell walls are thicket, meaning unable to undergo cytokinesis

32
Q

Give examples of meristems

A
  • Just behind root tips
  • just behind shoot tips
  • cambium
  • buds
33
Q

Compare cell division in plants and animal cells

A
  • no centrioles present vs centrioles present
  • cytokinesis starts from middle of the cell vs cytokinesis starts at edge of the cell
  • occurs at meristems vs occurs throughout the body
34
Q

How do yeast cells reproduce

A

Budding/asexual reproduction

35
Q

Describe the process of cell division in yeast cells

A
  • nucleus divides by mitosis
  • cell swells on the side (bud develops)
  • one nucleus moves into the swelling
  • unequal distribution of cytoplasm
  • cell wall forms
  • two new cells formed (genetically identical)
36
Q

How do prokaryote cells divide

A

Binary fission

37
Q

Describe cell division in prokaryote cells

A
  • the cell grows to its limit
  • DNA replicates
  • two new loops of DNA pulled to opposite poles of the cell
  • cell divides into 2
  • a new cell wall forms
38
Q

What organelles within eukaryotes divide by binary fission

A

Chloroplasts, mitochondria