CCS Transplant 2020 Flashcards
What are three frailty assessment tools?
- Fried index (3 or more)
- Deficit Index
- Edmonton Frailty Scale
What is BMI cut off (relative CI)
BMI > 35
Name 5 desensitizing agents for high PRA?
PLEX
IVIG
Rituximab
Bortezomib
Eculizimab
What are the two recommended agents for immunosuppression?
- CNI (Tac > Cyclosporine)
- MMF
What to do with CNI/MMF maintenance therapy when Cancer diagnosed?
-Reduce maintenancy therapy and add Sirolimus
What is time frame to wean cortocosteroids post transplant?
Within 1 year
How to treat 2R rejection if Asymptomatic?
Oral corticosteroids
How to treat 3R or symptomatic 2R?
IV Pulse steroids
When to repeat EMB after Cellular rejection treated?
7-14 days
When to treat AMR?
pAMR 2 or more, with graft dysfunction and or symptoms
How to treat AMR?
IV steroids
Or PLEX
Or IVIG
What are the two first line agents for hypertension? (benefit for CAV)
- ACEi
- CCB
What is routine screening for transplant patients?
- Cervical, colon, prostate, breast ca
- annual skin cancer
Who needs CMV prophylaxis?
- D+/R-
- Receptor+
What is used for CMV prophylaxis?
Valgan for 3-6 months