CCB Flashcards
1
Q
Names
A
Nifedipine,
Verapamil
Diltiazem
Amlopidine
2
Q
MOA
A
Blocks voltage dependent L type channel of cardiac and smooth muscle
3
Q
Specificity
A
Vascular smooth muscle:
amlodipine/nifedipine > diltiazem > verapamil
(-pine=peripheral)
Heart:
verapamil>diltiazem>amlodipine/nifedipine
(verapamil=ventricle)
4
Q
Use
A
HTN, angina, arrhythmias (not nifedipine)
Prinzmetal’s angina, Raynauds
5
Q
Toxicity
A
Cardiac depression AV block Peripheral edema Flushing Dizziness Constipation