CCB Flashcards

1
Q

Names

A

Nifedipine,
Verapamil
Diltiazem
Amlopidine

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2
Q

MOA

A

Blocks voltage dependent L type channel of cardiac and smooth muscle

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3
Q

Specificity

A

Vascular smooth muscle:
amlodipine/nifedipine > diltiazem > verapamil
(-pine=peripheral)

Heart:
verapamil>diltiazem>amlodipine/nifedipine
(verapamil=ventricle)

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4
Q

Use

A

HTN, angina, arrhythmias (not nifedipine)

Prinzmetal’s angina, Raynauds

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5
Q

Toxicity

A
Cardiac depression
AV block
Peripheral edema
Flushing
Dizziness
Constipation
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