Care of patients with ACS Case studies Flashcards
Single largest killer of American men and women in all ethnic groups
Broad term that includes chronic stable angina and acute coronary syndromes (unstable angina - STEMI and NSTEMI)
Affects the arteries that provide blood, oxygen, and nutrients to the myocardium (heart muscle)
Ischemia occurs when insufficient oxygen is supplied to meet the requirements
Infarction (necrosis or cell death) occurs when severe ischemia is prolonged over long-period time and decreased perfusion causes irreversible damage to tissue - can develop HF as a result; no blood flow to heart can die; need recognize early MI early and assess ASAP
Coronary artery disease (CAD)
atherosclerosis is the primary factor in the development of CAD; nonmodifiable and modifiable risk factors contribute to atherosclerosis
Nonmodifiable: age, gender, family history - may need screen earlier, ethnic background
Modifiable: elevated serum lipid levels, smoking, limited physical activity, HTN, DM, obesity, excessive alcohol, excessive stress/decreased coping skills - focus on these: any meds and importance staying on med regimen
Etiology: CAD risk factors
Chest pain caused by a temporary imbalance between the coronary arteries’ ability to supply oxygen and the cardiac muscle’s demand for oxygen
Ischemia (lack of oxygen) that occurs is limited in duration and does not cause permanent damage
Two types:
Angina pectoris
Chronic stable angina
Unstable angina - ACS
Two types:- Angina pectoris
Chest discomfort that occurs with moderate to prolonged exertion in a pattern that is familiar to the patient
Frequency, duration, and intensity of symptoms remain the same over several months
Results in only slight limitation of activity and is usually associated with a fixed atherosclerotic plaque
Usually relieved by nitroglycerin or rest; managed with drug therapy
Less than 15 min
Affecting daily life
Chronic stable angina
Term used to describe patients who have either unstable angina or acute myocardial infarction
Atherosclerotic plaque in the coronary artery ruptures, resulting in platelet aggregation (clumping), thrombus (clot) formation, and causes vasoconstriction/totally occlude vessel and cut off vessel
ACS classified into one of three categories according to the presence or absence of ST-segment elevation on the ECG and positive serum troponin markers:
Acute coronary syndromes
ST-elevation MI (STEMI), traditional manifestation
Non-ST-elevation MI (NSTEMI), common in women
Unstable angina pectoris
ACS classified into one of three categories according to the presence or absence of ST-segment elevation on the ECG and positive serum troponin markers:
Chest pain or discomfort that occurs at rest or with exertion and causes severe activity limitation
Pressure may last longer than 15 minutes
Poorly relieved by rest or nitroglycerin
May present with ST changes but do not have changes in troponin or creatine kinase (CK) levels
May include:
Unstable angina pectoris
New-onset angina –
Variant (Prinzmetal’s) angina –
Pre-infarction angina –
May include:- Unstable angina pectoris
describes the patient who has his or her first angina symptoms, usually after exertion or other increased demands on the heart
First episode
New-onset angina –
chest pain or discomfort resulting from acute coronary artery spasm and typically occurs after rest
Variant (Prinzmetal’s) angina –
refers to chest pain that occurs in the days or weeks before an MI
Pre-infarction angina –
Reduces peripheral vasoconstriction and oxygen demand
Relieves episodic anginal pain
Tablet or spray can be administered every 5 minutes for a total of 3 doses
Drop BP low because vasodilator
Can be given IV
Patient may experience a headache - taken a lot might not experience anymore
Nitroglycerin
Occurs when myocardial tissue is abruptly and severely deprived of oxygen
When blood flow is quickly reduced by 80% to 90%, ischemia develops
Ischemia can lead to injury and necrosis of myocardial tissue if blood flow is not restored
Evolves over a period of several hours
Extent of infarction depends on collateral circulation, anaerobic metabolism, and workload demands: stents, grafting; restore blood flow: if occluded s/s of not having adequate blood flow
Physical changes do not occur in the heart until 6 hours after the infarction; evolves over sev hours; diff types heart attacks depending on location and how much occlusion
Once infarction occurs, scar tissue permanently changes the size and shape of the entire left ventricle, called ventricular remodeling - LV has irreversible damage develops HF; LV not same as was before
Myocardial infarction (MI/AMI)
Pain or discomfort
Frequent associated symptoms:
Key features of MI
Substernal chest pain/pressure radiating to the left arm
Pain or discomfort in jaw, back, shoulder, or abdomen
Occurring without cause, usually in the morning
Relieved only by opioids
Lasting 30 minutes or more
Pain or discomfort - Key features of MI
N/V
Diaphoresis
Dyspnea
Feelings of fear or anxiety
Dysrhythmias
Fatigue
Palpitations - heart beating really fast
Epigastric distress
Anxiety
Dizziness
Disorientation/acute confusion - depending on blood flow and how much O2 getting
Feeling “short of breath”
Frequent associated symptoms: - Key features of MI
NSTEMI – non-ST-segment elevation myocardial infarction
ST and T-wave changes on an ECG; not elevation
Indicates myocardial ischemia
Cardiac enzymes may be initially normal but elevate over the next 3 to 12 hours; negative troponin; always trend troponins and start going up sometimes
Causes: coronary vasospasm, spontaneous dissection, sluggish blood flow due to narrowing of the coronary artery - not total occlusion
NSTEMI
STEMI – ST-elevation myocardial infarction in at least 2 leads
ST elevation in two leads on a ECG
Indicates myocardial infarction/necrosis
Attributable to rupture of the fibrous atherosclerotic plaque leading to platelet aggregation and thrombus formation at the site of rupture - completely occluding blood flow
Thrombus causes an abrupt 100% occlusion to the coronary artery - not perfusing and have s/s and need do intervention quickly
STEMI
Troponin
Creatine kinase (CK)
CK-MB
MI Laboratory assessment
Myocardial muscle protein released when there is injury to myocardial muscle; drawn suspect MI
Troponins T and I are not found in healthy patients
Any rise in value indicates cardiac necrosis or myocardial injury
Assess labs at 0, 3, 6 hours or until value peaks - want see how high went
Troponin
Enzyme specific to cells of the brain, myocardium, and skeletal muscle
CK indicates tissue necrosis or injury
Creatine kinase (CK)
Specially found in myocardial muscle
Not as quick as troponin
CK-MB
Thallium scans
Contrast-enhanced cardiovascular magnetic resonance (CMR)
Echocardiogram - HF post-MI; see if any damage to muscle tissue
Computed tomography coronary angiography (CTCA)
Imaging assessment