Assessment of the Hematologic System Flashcards

1
Q

Responsible for blood formation
First produces blood stem cells
Red blood cells (RBCs, erythrocytes)
White blood cells (WBCs, leukocytes)
Platelets
Also has role in immune responses
Located in flat bones (sternum, skull, pelvic and shoulder girdles) and ends of long bones

A

Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Stem cells (immature)are capable of becoming any type of blood cell, depending on the body’s needs

A

First produces blood stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Composed of plasma and cells
Plasma is an extracellular fluid with plasma proteins (3 main)
Blood cells

A

Blood components

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Albumin: maintain osmotic pressure of blood - prevents plasma from leaking into tissues
Globulins: transport of antibodies - Ig
Fibrinogen: important in clotting

A

Plasma is an extracellular fluid with plasma proteins (3 main)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Largest proportion of blood cells
Produce hemoglobin which carries oxygen and carbon dioxide
Iron is important component of hemoglobin - allows carry O2

A

RBCs - Blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Role in inflammation and infection protection

A

WBCs - Blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Smallest blood cell
Clotting and bleeding
Stick to injured vessel walls and aggregate to assist clotting
Stim IR - clump together and plug the hole
Stored in spleen

A

Platelets - Blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Destroys old or imperfect RBCs
Breaks down the hemoglobin
Something wrong increased risk of bleeding
Stores platelets
Antibody production and filters antigens
After a splenectomy patients have reduced immune functions - increased risk for infection; decreased antibody production and ability filter them

A

Spleen - Accessory organs of blood formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Produces prothrombin and other blood clotting factors
Assists in the forming of Vitamin K in the intestines - clotting
Stores all blood cells
Stores iron in the form of ferritin

A

Liver - Accessory organs of blood formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Decreased blood volume
Lower levels of plasma proteins
Bone Marrow produces less blood cells
Hemoglobin levels in men and women fall after middle age
Immune responses change

A

Hematologic changes associated with aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Could be related to decrease in protein intake
Higher risk for infections, bleeding, edema

A

Lower levels of plasma proteins - Hematologic changes associated with aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

RBC and WBC counts decrease
Platelet counts do not change with age

A

Bone Marrow produces less blood cells - Hematologic changes associated with aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Could be related to decrease in iron intake

A

Hemoglobin levels in men and women fall after middle age - Hematologic changes associated with aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

WBC counts may be lower
WBC count does not rise as high in response to infection in older adults - not as responsive
Presentation of infection diff
Antibody levels and responses are lower and slower in older adults
Lymphocytes become less reactive to antigens

A

Immune responses change - Hematologic changes associated with aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Patient history
Nutritional status - iron and vitamin B12
Environmental exposure - toxin
Family history and genetic risk
Current health problems

A

Assessment methods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Age - older
Gender
Liver function - symp liver disease, alcohol use
Presence of known immunologic or hematologic disorders
Drug use

A

Patient history

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Females have lower red blood cells - H/H; worse when menstruating; worse fluid retention

A

Gender

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Some medications can cause bone marrow suppression, hemolysis, or disrupt platelet action or clotting factors

A

Drug use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Many disorders are inherited
Ex. Sickle cell, hemophilia

A

Family history and genetic risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Lymph node swelling
Excessive bruising or bleeding
Common symptoms with hematological disease:
Most common manifestation of anemia is fatigue as a result of decreased oxygen delivery to cells (SOB too)

A

Current health problems

21
Q

shortness of breath on exertion
Palpitations
frequent infections
Fevers
recent weight loss
Headaches
Paresthesia - abnormal sensation

A

Common symptoms with hematological disease:

22
Q

Skin - BIG
Head & Neck
Respiratory
Cardiovascular
Kidney & Urinary
Musculoskeletal
Abdominal
Central Nervous System

A

Phys assessment

23
Q

Inspect skin and mucous membranes for pallor
Assess nail beds for pallor or cyanosis: Pallor of the gums, conjunctivae, and palmar creases indicates decreased hemoglobin levels and poor tissue oxygenation
Inspect for petechiae and ecchymoses

A

Skin - BIG

24
Q

Check for pallor or ulceration of the oral mucosa
Inspect and palpate all lymph node areas

A

Head & Neck

25
Q

Assess respirations and dyspnea at rest and on exertion - decreased RBC and Hgb
Assess for fatigue - anemia
Orthopnea

A

Respiratory

26
Q

Assess pulses
BP
Abnormal heart sounds
Irregular rhythms
Perfusion

A

Cardiovascular

27
Q

Assess urine for hematuria - increased risk for bleeding
CKD - EPO

A

Kidney & Urinary

28
Q

Rib or sternal tenderness may occur with leukemia
Assess range of joint motion, document any swelling or joint pain

A

Musculoskeletal

29
Q

Evaluate spleen
Stool specimen to check for occult blood testing

A

Abdominal

30
Q

Normal adult spleen is usually not palpable
Enlarged spleen may occur with many hematologic problems - thing prb and enlarged not palpate because rupture

A

Evaluate spleen

31
Q

Neurologic checks and checks of cognitive function - anemia and resp issue

A

Central Nervous System

32
Q

4.2-6.1
Decreased: possible anemia/hemorrhage
Increased: possible chronic hypoxia/polycythmeia vera - overproduction all blood cells

A

Red blood cell (RBC) count - Lab profile

33
Q

12-18 g/dL
Decreased: possible anemia/hemorrhage
Increased: possible chronic hypoxia/polycythmeia vera - overproduction all blood cells

A

Hgb - Lab profile

34
Q

37-52%
Decreased: possible anemia/hemorrhage
Increased: possible chronic hypoxia/polycythmeia vera - overproduction all blood cells

A

Hct - Lab profile

35
Q

5000-10000
Decreased: prolonged infection/bone marrow suppression
Increased: infection, inflammation, autoimmune disorders, leukemia

A

WBC count - Lab profile

36
Q

150,000-400,000
Decreased: bone marrow suppression, autoimmune disease, hypersplenism
Increased: polycythmeia vera - overproduction all blood cells/malignancy

A

Platelet count - Lab profile

37
Q

11-12.5 sec
Decreased: vitamin K excess
Increased: possible deficiency of clotting factors V and VII

A

Prothrombin time (PT) - Lab profile

38
Q

60-180 mcg/dL
Decreased: iron deficiency anemia, hemorrhage
Increased: iron excess, liver disorders, hemochromatosis, megaloblastic anemia

A

Iron - Lab profile

39
Q

10-300 ng/mL
Decreased: iron deficiency anemia, hemorrhage
Increased: iron excess, liver disorders, hemochromatosis, megaloblastic anemia

A

Ferritin - Lab profile

40
Q

250-460 mg/dL
Increased: iron deficiency anemia - More iron binding capacity - not getting to where need be
Decreased: anemia, hemorrhage, hemolysis

A

Total iron-binding capacity - Lab profile

41
Q

Evaluates hematologic status
Invasive procedure - not first thing; after lab work
Aspiration
Biopsy
Informed consent needed
Preparation:
Post procedure care:

A

Bone marrow aspiration and biopsy

42
Q

Specifically for a possible problem in blood cell production or maturation

A

Evaluates hematologic status

43
Q

cells and fluids are suctioned from the bone marrow

A

Aspiration

44
Q

solid tissue and cells are obtained by coring out an area of bone marrow with a large-bore needle

A

Biopsy

45
Q

Provide information and emotional support - anxious or fearful during pain - local anesthetics: some pressure experience
Explain the procedure
Positioning

A

Preparation:

46
Q

Local anesthetic is used and may feel stinging or burning sensation
Mild tranquilizer or a rapid-acting sedative could be used
Expect a heavy sensation of pressure and pushing while the needle is being inserted
Procedure quickly

A

Explain the procedure

47
Q

Usually use the iliac crest
Patient should be placed in the prone or side-lying position

A

Positioning

48
Q

Hold pressure briefly to site
Cover the site with a dressing after bleeding is controlled - monitor for bleeding
Give mild analgesic for discomfort
Apply ice bag to the needle site to limit bruising - help for pain
Observe site every 2 hours for 24 hours for signs of bleeding, bruising, and infection - check sight frequently
Advise the patient to avoid contact sports or any activity that might result in trauma to the site for 48 hours

A

Post procedure care: