Cardiovascular + Renal system - #2 Flashcards

1
Q

What is an IHD?

A

ischemic heart disease - It’s the term given to heart problems caused by narrowed heart arteries. When arteries are narrowed, less blood and oxygen reaches the heart muscle. This is also called coronary artery disease and coronary heart disease. This can ultimately lead to heart attack.

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2
Q

What are some modifiable risk factors for IHD (Ischemic heart disease)?

A

The risk factors that can be controlled (modifiable) are: High BP; high blood cholesterol levels; smoking; diabetes; overweight or obesity; lack of physical activity; unhealthy diet and stress.

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3
Q

What are some non-modifiable risk factors for IHD (Ischemic heart disease)?

A

non-modifiable risk factors are: age ethnic background family history of heart disease. The older you are, the more likely you are to develop coronary heart disease or to have a cardiac event (angina, heart attack or stroke).

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4
Q

What is the aim of cardiac rehabilitation?

A

The main goals of cardiac rehabilitation are: to prevent you suffering further cardiovascular events by helping you take control of your life to improve your quality of life.

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5
Q

How does a myocardial infraction lead to heart failure?

A

Heart failure developing after MI hospitalization is a consequence of cardiomyocyte death and scar formation, which triggers chronic neurohumoral activation (renin–angiotensin–aldosterone and sympathetic nervous system up-regulation) and ventricular remodelling.

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6
Q

What is the difference between HFrEF and HFpEF?

A

The key difference between HFpEF and HFrEF is that HFpEF (heart failure with preserved ejection fraction) takes place when the left ventricle fails to fill properly during diastolic phase while HFrEF (heart failure with reduced ejection fraction) takes place when the heart muscles fail to squeeze properly to pump an adequate amount of oxygen-rich blood to other parts of the body during systolic phase.

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7
Q

What are some compensatory mechanisms that are initiated in HF?

A

The compensatory mechanisms that have been described thus far include: activation of the sympathetic (adrenergic) nervous system (SNS) and renin–angiotensin–aldosterone system (RAAS).

which maintain cardiac output through increased retention of salt and water, peripheral arterial vasoconstriction and increased contractility; and inflammatory mediators1 that are involved in cardiac repair and remodelling.

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8
Q

What does ACS stand for and what does it describe?

A

Acute coronary syndrome

a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart.

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9
Q

Which conditions are included under the term ACS?

A

Types of ACS are:

Unstable angina: This involves sudden, unexpected chest pain or pressure, even while resting. It’s a warning sign of a heart attack and occurs when stable angina worsens.

Non-ST-elevation myocardial infarction: An NSTEMI is a heart attack that providers can detect with blood tests but not with an electrocardiogram (EKG). It means your coronary arteries aren’t fully blocked or were blocked for a short amount of time.

ST-elevation myocardial infarction: A STEMI is a much more severe heart attack that providers can detect with blood tests and EKG. It occurs when blood flow to your heart is fully blocked for a long time, affecting a large part of your heart.

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10
Q

What is an Unstable angina?

A

a condition in which your heart doesn’t get enough blood flow and oxygen. It may lead to a heart attack. Angina is a type of chest discomfort caused by poor blood flow through the blood vessels (coronary vessels) of the heart muscle (myocardium).

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11
Q

What is angina?

A

Angina is a type of chest discomfort caused by poor blood flow through the blood vessels (coronary vessels) of the heart muscle (myocardium).

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12
Q

What is an Non-ST-elevation myocardial infarction?

A

An NSTEMI is a heart attack that providers can detect with blood tests but not with an electrocardiogram (EKG). It means your coronary arteries aren’t fully blocked or were blocked for a short amount of time.

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13
Q

What is a ST-elevation myocardial infarction?

A

A STEMI is a much more severe heart attack that providers can detect with blood tests and EKG. It occurs when blood flow to your heart is fully blocked for a long time, affecting a large part of your heart.

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14
Q

What is the difference between angina, MI, and cardiac arrest.

A

Angina is a type of chest pain as a result of narrowed coronary arteries.

MI is the result of blocked coronary arteries causing permanent heart damage. “Circulation” problem.

Cardiac arrest when the heart malfunctions and suddenly stops beating unexpectedly. “Electrical” problem.

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15
Q

What is ejection fraction?

A

Ejection fraction (EF) is a measurement, expressed as a percentage, of how much blood the left ventricle pumps out with each contraction.

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16
Q

What is left-sided heart failure?

A

Where your left ventricle is unable to pump blood adequately and blood builds up in the pulmonary veins

There are two types of left-sided heart failure:

Systolic failure. This is when your left ventricle isn’t able to contract normally and your heart can’t push an adequate amount of blood into circulation.
Diastolic failure. This means your left ventricle doesn’t relax properly due to stiffness and your heart doesn’t fill with enough blood between beats, or the pressure for the heart to function is very high.

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17
Q

What is right-sided heart failure?

A

Right-sided heart failure is where the right ventricle cant pump blood properly through the veins leading to blood buildup, which in turn may lead to fluid retention and swelling. The legs are the most common area to develop swelling, but it’s also possible to develop it in your genitals and abdomen.

Right-sided heart failure most often develops from left-sided heart failure due to a backup of blood around your lungs that puts more stress on the right side of your heart.

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18
Q

What is congestive heart faliure?

A

Congestive heart failure (CHF) is a chronic progressive condition that affects the pumping power of your heart muscle. Where fluid builds up within the heart and causes it to pump inefficiently.

19
Q

What are the common causes of L)HF?

A

coronary artery disease, heart attack, arrhythmia or long-term high blood pressure

20
Q

What are the common causes of R)HF?

A

left-sided heart failure and some lung diseases such as chronic obstructive pulmonary disease

21
Q

Which is more common, L)HR or R)HF?

A

L)HF

22
Q

What are the hallmark symptoms of L)HF?

A

Tends to cause lung congestion and symptoms that affect your breathing

23
Q

What are the hallmark symptoms of R)HF?

A

often causes fluid retention in your legs or other parts of your body

24
Q

What would we label a heart rate that is over 100?

A

Tacycardic

25
Q

What do we mean by “This patient is tachycardic”?

A

This patient has a heart rate that is over 100 beats per minute

26
Q

A STEMI (ST-elevation myocardial infarction) results in what?

A

Myocardial cell death, reduced myocardial contractility, and reduced Cardiac output. I.e this results in the myocardium not pumping as efficiently as it should be

27
Q

When a patient has had or is having a STEMI, they will have reduced cardiac output due to reduced myocardial contractility - how does the body respond to try increase cardiac output?

A

In an attempt to maintain adequate CO, the SNS and RAAS respond, causing an increase in heart rate, respiratory rate, and decrease in urinary output.

28
Q

What does UO stand for?

A

Urinary output

29
Q

What does RAAS stand for and what is it?

A

renin–angiotensin–aldosterone system (RAAS)

it is a critical regulator of blood volume and systemic vascular resistance

30
Q

What does STEMI stand for?

A

ST-elevation myocardial infarction

31
Q

What is a STEMI?

A

A heart attack with a completely blocked coronary artery

32
Q

How may shortness of breath and a cough relate to L)HF?

A

When the left side is not pumping correctly, blood backs up in the blood vessels of the lungs causing increased hydrostatic pressure. Due to hydrostatic pressure, fluid from the blood is forced into the lungs impairing gas exchange.

33
Q

What is hydrostatic pressure?

A

The force of hydrostatic pressure means that as blood moves along the capillary, fluid moves out through its pores and into the interstitial space. This movement means that the pressure exerted by the blood will become lower, as the blood moves along the capillary, from the arterial to the venous end.

34
Q

What is the difference between acute kidney injury, and chronic kidney disease?

A

Acute kidney injury = sudden = occurs in phases
Chronic kidney disease = occurs over time = occurs in stages

Acute kidney injury (AKI) occurs when the kidneys suddenly fail due to an injury, medication, or illness. Chronic kidney disease (CKD) is the gradual loss of kidney function mainly caused by high blood pressure, diabetes, and an inflammatory condition.

35
Q

Which one can a patient recover from? AKI or CKD?

A

A patient can recover from an Acute Kidney Injury (AKI)

36
Q

Early prevention of an AKI (acute kidney injury) prevents what?

A

Mortality and end stage kidney disease (ESKD)

37
Q

ESKD (End stage kidney disease) requires what treatment?

A

Renal replacement therapy (RRT) dialysis, or transplantation

38
Q

How can the abuse of caffeine impact the kidneys?

A

Caffeine is a mild diuretic and will lead to a mild increase in urine output for a short time. Caffeine will also raise blood pressure slightly for a short time. If a patient is overweight/obese and has metabolic syndrome caffeine will likely decline their eGFR i.e decline renal function.

39
Q

What does a diuretic do to the kidneys?

A

They help rid your body of salt (sodium) and water. Most of these medicines help your kidneys release more sodium into your urine. The sodium helps remove water from your blood, decreasing the amount of fluid flowing through your veins and arteries. Hence, this reduces blood pressure.

40
Q

What is the main goal of dialysis?

A

To remove toxins

41
Q

Can dialysis preform all of the kidneys functions?

A

No its main goal is to remove toxins.
It cant control blood pressure and release hormones ect.
Hence they will still need to regulate fluids and diet ect.

42
Q

What happens if you abuse diuretics?

A

Diuretic abuse can lead to severe hyponatremia. Hyponatremia occurs when the concentration of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that’s in and around your cells, thereforce can lead to fluid build up in the body.

43
Q

Whats the difference between cardiac arrest and a myocardial infraction?

A

A heart attack, technically called a myocardial infarction or MI, happens when there is a blockage that prevents the oxygen-rich blood from getting to the heart

Cardiac arrest is when the heart suddenly stops functioning.