Blue Box Diagrams Flashcards
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What are the Adverse Effects?
Toxicity with prolonged exposure to high O2 concentrations
Decreased affinity of Hb for CO2 in CO2 retainers (Haldane effect)
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What are the precautions?
Oxygen therapy devices should not be used near an open flame due to its high combustibility
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What are we monitoring?
Sp02, RR, PaO2 (ABG), colour.
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What patient education are we giving?
Correct administration and use of oxygen delivery devices.
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What are we treating?
Treatment of hypoxaemia by increasing alveolar O2 tension. The aim is achieve a normal or near normal oxygen saturation for an individual patient.
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What is the pharmacodynamics behind this drug?
Oxygen therapy improves effective cellular oxygenation. It acts to restore normal cellular activity at the mitochondrial level and reduce metabolic acidosis.
When administering a drug as an RN you will need to be aware of the following:
Drug: O2
What is the pharmacokinetics behind this drug?
Oxygen is largely inhaled into the alveoli and diffuses into the capillary bed. Oxygen combines with haemoglobin, with a small amount being dissolved in the plasma. Oxygen is metabolised in the tissues almost entirely in the mitochondria, where oxidative enzymes reduce the oxygen in the formation of adenosine triphosphate (ATP). Excretion of oxygen metabolites (CO2 and H20) is via the lung and renal system.
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What is the pharmacokinetics behind this drug?
Onset by inhalation is rapid (5-15mins).
Peak effect reached in 1-2 hours.
Metabolised in liver and excreted in the kidneys.
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What is the pharmacodynamics behind this drug?
Salbutamol is a B2-adrenergic agonist and stimulates B2-adrenergic receptors. Binding to these receptors in the lungs results in relaxation of bronchial smooth muscles.
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What is the goal of this drug?
It is a bronchodilator that works to relief symptoms during maintenance treatment of asthma and COPD; and prevention or treatment of exercise/allergen induced bronchospasm.
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What are the adverse effects of this drug?
Tachycardia, headache, nervous tension, fine hand tremor, hypotension
Hyper/hypokalaemia (which may cause weakness, fatigue, tremors, and muscle spasm)
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What is the required patient education for this drug?
Common side effects to expect
Appropriate delivery of the inhaler (inc spacer and mouth care)
and
Asthma & COPD action plans
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What are some contraindications of this drug?
Caution with CVD, diabetes, and HTN
Inhaler may also contain lactose
When administering a drug as an RN you will need to be aware of the following:
Drug: Salbutamol (short acting B2 adrenergic agonist SABA)
What are the monitoring requirements of this drug?
Peak flow measurements before and after administration can help determine effectiveness.
What are the common side effects of omeprazole (losec)?
Abdominal pain, constipation, diarrhoea, flatutence, nausea, and vomiting along with headaches
What are some significant drug interactions to be aware of for Omeprazole (Losec)?
Diazepam
Ketoconazole
Litraconazole
Digoxin
What kind of medication is omeprazole (losec)?
Proton pump inhibitor (PPI)
What are the pharmacodynamics of Omeprazole?
They suppress gastric acid secretion by inhibiting the hydrogen - potassium adenosine triphosphatase (ATPase) enzyme system at the secretory surface of the gastric parietal cells.
What is the pharmacokinetics of Omeprazole (Losec)?
PO, half-life somewhere between 30mins and 2 hours with the duration of action. (3-5 days)
What do we need to monitor for, with a patient taking omeprazole (losec)?
Watch for worsening symptoms of an underlying condition
What is the patient education required for a patient taking omeprazole (losec)?
Take missed dose as soon as remembered (do not double dose), store under 25 degrees, and be aware a rebound effect may occur
What is a rebound effect?
Rebound effects are the transient return of symptoms for which a medication has been prescribed (e.g., insomnia or anxiety)
What are the side effects of GTN (Glyceryl Trinitrate Antianginal)?
Flushing, Headache, Dizzyness, and rarely dry mouth
What are the contra-indications for GTN?
Viagra, ETOH, and a heart rate of below 50bpm.
What are the pharmacodynamics for GTN?
Antagonises NO receptors = relaxes smooth muscle. This dilates the veins and arteries hence reducing BP
What are the pharmacokinetics of GTN?
Sublingual and dermal, with a rapidly metabolised short duration
What’s the indications of use for GTN?
Chest pain/angina
What are the monitoring requirements for while a patient is taking GTN?
BP and HR
What is the patient education for GTN?
Advise the patient to rest and stay sitting while taking the medication, if standing after do so slowly.
What are the indications of use for morphine sulfate?
Analgesia/sedation