Cardiovascular + Renal system - #1 Flashcards
What is a PCI?
Percutaneous Coronary Intervention
(PCI, formerly known as angioplasty with stent) is a non-surgical procedure that uses a catheter (a thin flexible tube) to place a small structure called a stent to open up blood vessels in the heart that have been narrowed by plaque buildup, a condition known as atherosclerosis.
What is atherosclerosis?
a disease of the arteries characterized by the deposition of fatty material on their inner walls.
What does HF stand for?
Heart Failure
Why do the kidneys reduce urine production and retain fluid in heart failure?
When the heart is unable to pump forcefully, the amount of blood it ejects with each contraction drops. This reduces the amount of blood that passes through the kidneys, causing urine and waste output to drop. i.e renal perfusion falls (The kidneys require blood flow to be able to pump urine out of the body)
What are 3 mechanisms the heart uses to compensate for the reduced blood flow through the body in heart faliure? (COME BACK TO ANSWER THIS ONE)
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The kidney is responsible for?
Acid-base balance Water balance Electrolyte regulation Toxin removal BP regulation Erythopoiteine production (RBC production in the bone marrow) Vitamin D activation.
What is GFR?
Glomerular filtration rate - the amount of blood that passes through the glomeruli each minute
What is the normal blood flow through the kidneys?
105-125mls/min (99% is reabsorbed resulting in 1-1.5L of urine per 24hrs)
What is eGFR?
The estimated GFR - Glomerular filtration rate
What are the pre-renal factors needed for urine production?
Adequate perfusion pressure (renal blood flow) and oxygenation of kidneys
What are the renal factors needed for urine production?
The kidney units must be functioning properly (no damage to the structures of the kidneys such as tubules and glomerulae)
What are the post-renal factors needed for urine production?
There must be no obstruction to urine flow
What is Oliguria?
An early warning sign related to poor urine output - 100-400ml/day (should be 1-1.5L per day)
What is Anuria?
Late warning sign related to poor urine output - >100/day (should be 1-1.5L per day)
What is absolute anuria?
Nil urine output/day
Two hours of oliguria can cause what?
Acute kidney injury
Acute kidney injury occurs when?
The kidneys are unable to remove the bodys metabolic waste or preform their seven regulatory functions. These metabolic wastes then build up in the body. and GFR falls as disease progresses.
What are glomeruli?
Glomeruli are the tiny network of blood vessels that are the “cleaning units” of your kidney. They filter waste and remove extra fluids from your blood. When glomeruli are damaged and can’t function as they should, it’s called glomerular disease.
How do kidney tubules work?
The tubule returns needed substances to your blood and removes wastes. A blood vessel runs alongside the tubule. As the filtered fluid moves along the tubule, the blood vessel reabsorbs almost all of the water, along with minerals and nutrients your body needs. The tubule helps remove excess acid from the blood.
Rapid loss of renal function due to kidney damage can be what?
Life threatening
Causes of prerenal acute kidney injury include what?
Low cardiac output, low blood pressure, and severe vomiting
Causes of postrenal acute kidney injury include what?
Obstruction and renal calculi
What is renal calculi?
A small, hard deposit that forms in the kidneys and is often painful when passed. Also called a kidney stone