cardiovascular 1: arteries Flashcards
what us the main cause of death in western countries
cvd(obviously like thats what these slides are about)
what are the layers of an artery and including non cell layers, how many are there
tunica intima
tunica media
tunica adventitia
3
what is the structure of the tunica intima
single layer of epithelial cells
endothelium
physical barrier
thin layer of connective tissue and elastic lamina
acts as a support for endothelium
what are the functions of the endothelium
controls movement of substances to blood to tissue and vice versa
acts as a physical barrier
regulates vascular function
dilation and restrictions using muscle (nitric oxide)
inflammatory response
what is the structure and function of the tunica media
middle layer
smooth muscle cells for vasoconstriction
extracellular matrix as a scaffold
what is the structure and function of the tunica adventitia
outer layer
compost of fibroblasts and connective tissue
large vessels have own blood supply
what causes atherosclerosis
deposition of lipids on arterial wall
what is the common structure of lipoproteins
spherical
lipid core
outer layer of phospholipids and apolipo protiens
what are the types of lipoprotiens by size
chylomicrons
very ldl
intermedia dl
ldl
hdl
what are cylomicrons and where are they found
made in the intestine and secreted into blood
deliver dietary fats to periferal tissues
tissues use the lipids and remnants cleared by liver
what are vldl and where are they found
made in liver
converted to idl and LDL in blood tissues and liver
what is apo b100
its a receptor that allows ldl to be taken from the bloodstream
what is hyperlipidemia
accumulation of ldl in the blood and deposition on walls
what is the name of the process by with hdl uptakes excess lipids
reverse cholesterol transport
