diabetus Flashcards
what is the split between type 1 and two diabetes
type 1:10
type 2:90
what are the conditions for diabetes diagnosis based on fasting blood glucose and gycated haem
fasting blood glucose >7nM
glycated haemoglobin >6.5
what is glycated haemoglobin
slow process that occcurs when haemoglobin is exposed to high blood suagr
what causes type 1 diabetes
autoimmune destruction of pancreatic beta islet cells
when was insulin discovered
in 1921, banting and best ground up dog pancreases and made an extract
how many people in the uk have type 2 and how many hospital beds
over three million
15%
what two condition can poor control of blood sugar cause
hypo and hyperglycemia
what are some symptoms of diabetus
thirst hunger piss too hard and being tired
blindness
poor circulation, amputation
heart disease and stroke
what is the most common drug used to type 2 diabetes
how many people take it
metformin
150 mill
what does metaformin do
amp activated protien kinase
Lowers blood sugar (less liver glucose).
Improves insulin sensitivity.
Activates AMPK for energy balance.