Carbohydrates Flashcards

1
Q

What is the cori cycle?

A

The cycle that links glycolysis and gluconeogenesis

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2
Q

Name the two types of main carbohydrates

A

Monosaccharides and disaccharides

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3
Q

Give 3 examples of monosaccharide

A

Fructose
Glucose
Galactose

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4
Q

Give 3 examples of Disaccharide

A

Maltose
Sucrose
Lactose

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5
Q

What are gluco and hexokinase?

A

Isoenzymes

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6
Q

What do isoenzymes do?

A

Catalyse the same reaction

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7
Q

Where is glucokinase found?

A

The liver

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8
Q

When will glucokinase pick up glucose?

A

When glucose concentration is high

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9
Q

What is glycogen?

A

A polymer of glucose

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10
Q

For every molecule of glucose broken apart what is there a net gain of?

A

2 ATP, 2 NADH and 2 pyruvate

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11
Q

What can pyruvate be converted into?

A

Ethanol, lactate or CO2

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12
Q

What is lactate dehydrogenase used to do?

A

To convert lactate into pyruvate using NAD+

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13
Q

When does lactate dehydrogenase work?

A

During gluconeogenesis

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14
Q

How many of the 10 reactions in glycolysis are reversible?

A

7

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15
Q

What is the fate of absorbed galactose?

A

It joins the glycolysis cycle

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16
Q

What does the pentose phosphate pathway produce?

A

NADPH and pentose sugars

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17
Q

What are the pentose sugars and NADPH produced by the pentose phosphate pathway used for?

A

Nucleic acid synthesis

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18
Q

Which part of the pentose pathway phosphate pathway is reversible?

A

The non-oxidative part

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19
Q

What does NADPH link in the pentose pathway?

A

Anabolic and catabolic pathways

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20
Q

What are disaccharides formed from?

A

Monomers linked by glycosidic bonds

21
Q

What is maltose a break-down product of?

22
Q

What are the two monomers in Lactose?

A

Galactose

Glucose

23
Q

Which two glucose polymers does starch contain?

A

Amylose

Amylopectin

24
Q

Why are amylopectin and glycogen more readily synthesised and degraded?

A

They have many non-reducing ends

25
What are glycoproteins?
Proteins that have carbohydrates covalently attached
26
What is the digestive enzyme present in the mouth?
Salivary amylase
27
What does salivary amylase hydrolyse?
The alpha 1-4 bonds of starch
28
What are the main products of carbohydrate digestion?
Glucose Galactose Fructose
29
How is glucose absorbed?
Through an indirect ATP-powered process
30
What are disaccharidase deficiencies characterised by?
Abdominal distension | Cramps
31
What is the most common disaccharidase defiency?
Lactose Intolerance
32
Where are glucose monomers removed from during the degradation of glycogen?
The non-reducing ends of the glycogen molecule
33
Name the 2 main molecules that glycogen can become following degradation?
Glucose | Lactate
34
What is the deficiency involved in von Gierke's disease?
Liver G-6-P deficiency
35
What is the deficiency involved in McArdle's disease?
Skeletal muscle phosphorylase deficiency
36
What are the names given to the 2 main phases in glycolysis?
Preparatory phase | Payoff phase
37
How many ATP are gained in the payoff phase?
4 ATP
38
What is the catalyst for the phosphorylation of glucose?
Hexokinase
39
What molecule requires regeneration during glycoysis?
NAD+
40
Pyruvate is reduced to lactate via what process?
Fermentation
41
The reduction of pyruvate to lactate replenishes the store of what?
NAD+
42
In cells with access to oxygen, pyruvate is oxidised to form what?
Acetyl CoA
43
Gluconeogenesis usually occurs in the liver in the response to what?
Hormonal controls
44
What does the pentose phosphate pathway produce for all organisms?
NADPH
45
What does the adrenal cortex require NADPH for?
Steroid synthesis
46
Where does the krebs cycle take place?
In the mitochondrial matrix
47
Which enzyme produces acetyl Co-A from pyruvate?
Pyruvate Dehydrogenase
48
What is pyruvate dehydrogenase regulated by?
ATP
49
What is an amphibolic pathway?
A pathway that serves both catabolic and anabolic processes