Cancer Virology Flashcards

1
Q

how do viruses cause cancer?

A
  1. integrations that alter oncogenes/tumor suppressors or components of signal transduction pathways
  2. chronic activation of the inflammatory response
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2
Q

human papillomavirus (HPV) structure

A

naked, icosahedral

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3
Q

human papillomavirus (HPV) & malignancy

A

viral proteins E6 and E7 INHIBIT tumor-suppressor genes p53 and Rb

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4
Q

human papillomavirus (HPV) clinical course

A

*WARTS
*cervical cancer

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5
Q

human papillomavirus (HPV) vaccine

A

Gardasil

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6
Q

Merkel cell virus

A

causes SKIN cancer

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7
Q

human T-lymphotropic virus (HTLV-1)

A

causes LEUKEMIA

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8
Q

hepatocellular carcinoma - viral causes

A

Hep B and/or Hep C

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