Cancer Medicine Flashcards
Malignant
Multiply rapidly, invasive and infiltrative, undifferentiated, metastasize
Benign
Grow slowly, encapsulated, differentiated, don’t spread
What are some enviro carcinogens?
Chemical, radiation, viruses (RNA/DNA), oncogenes (rad/colon cancer,myc/lymphoma, and bcr-abl/ chronic myelogenous leukemia)
What are some hereditary carcinogens?
Retinoblastoma, polyposis coli, Wilm’s tumors, Ewig’s sarcomas
Neoplasm (tumors)
Growths that arise from normal tissue
What epithelial carcinomas are found in lung?
Adenocarcinoma (bronchioloaveolar), large cell, small (oat) cell, squamous cell (epidermoid)
What epithelial carcinomas are found in reproductive organs?
Adenocarcinoma of uterus, carcinoma of penis, choriocarcinoma of uterus/testes, cystadenocarcinoma (mucinous/serous) of ovaries, seminoma/embryonal cell carcinoma (testes), squamous cell (epidermoid) carcinoma of vag or cervix
What epithelial carcinomas found in skin?
Basal cell, malignant melanoma, squamous cell
Sarcomas
Connective tissue origin, 5% of all malignancies
Where are cystic tumors found?
Ovarian
Where are fungating tumors found?
Colon
Where are inflammatory tumors found?
Breast
Where are medullary tumors found?
Thyroid/breast
Where are necrotic tumors found?
Loss of blood supply
Where is a polypoid tumor found?
Colon
Where is an ulcerating tumor found?
Stomach
Verrucous
Wartlike (gingiva) tumors
Alveolar
Tumor cells form patterns resemble small sacs
Carcinoma in situ
Localized tumor cells not invaded adjacent structure
Diffuse
Spread evenly through affected tissue
Dysplastic
Containing abnormal-appearing cells not clearly cancerous
Epidermoid
Resembling squamous epithelial cells
Follicular
Forming small glandular sacs
Papillary
Small finger-like projections of cells
Pleomorphic
Composed of variety of cells
Scirrhous
Densely packed tumors, due to dense bands of fibrous tissue
Undifferentiated
Lacking microscopic structures typical of normal mature cells
Grade
Degree of maturity or differentiation under microscope
Stage
Extent of spread in the body
Core needle biopsy
Small sample from center
En bloc resection
Resection of large block of tumor and tissue (breast)
Excision biopsy
Removal and biopsy
Exenteration
Removal of organ
Fine needle aspiration biopsy
Fluid removal from lesion
Fulguration
High frequency electrical current
Incisional biopsy
Incision into a lesion or a specific part of a lesion
Brachytherapy
Radiation
Electron beams
Close to patient or implanted
External beam radiation (teletherapy)
Beam is far from patient
Fractionation
Radiation doses split into intervals
Gray (Gy)
Absorbed dose of radiation energy
Linear accelerator
Increases the velocity of subatomic particles
Photon therapy
The smallest unit of radiation therapy
Proton therapy
Uses protons, less damaging to other tissues
Radiocurable tumor
Tx may be radiation only
Radioresistant tumor
Self explanatory
Radiosensitive tumor
Appears to be sensitive to radiation
Radiosensitizers
Drugs that make cells more sensitive to radiation
Simulation
Use of computer to simulate the cancer scenario and tx
Stereotactic radiosurgery
Surgery using radiation to destroy the lesion
Alopecia
Baldness
Fibrosis
Increase in connective tissue
Infertility
Inability to conceive a child
Mucositis
Inflammation and ulceration of mucous membranes
Myelosuppression
Bone marrow depression
Secondary tumors
New types of tumors
Xerostomia
Dryness of mouth