Cancer

Question 1

Treatment of chronic myeloid leukaemia?

Answer 1

Imatinib (Tyrosine Kinase Inhibitor)

Question 2

What on a blood test could indicated lung cancer?

Answer 2

Raised platelets

Question 3

SCLC + lef weakness makes you think what?

Answer 3

Lambert Eaton syndrome

Question 4

HPV 6 & 11 bad or good?

Answer 4

Good (in relativity)
Only cause genital warts

Question 5

Cancerous HPV types?

Answer 5

16 & 18

Question 6

WHat type of cancer is schistosomiasis a RF for?

Answer 6

SCC of the bladder

Question 7

Pancreatic cancer invgX?

Answer 7

High res CT

Question 8

Blood film finding of CLL?

Answer 8

Smudge cells

Question 9

The is a greater/lesser risk if ovulation is not suppressed for ovarian cancer?

Answer 9

Greater

-Early menarche
-Late menopause
-Obesity
-Hormone replacement therapy

Question 10

What can NSAIDs increase the risk of in patients with chicken pox?

Answer 10

Nec Fasciitis

Question 11

What illicit drug can increase risk of serotonin syndrome in SSRI users?

Answer 11

MDMA

Question 12

What can be prevented by prescribing isoniazid and pyridoxine together?

Answer 12

Peripheral neuropathy

Question 13

Urge incontinence treatment in elderly people to avoid them becoming confused?

Answer 13

Mirabegron instead of oxybutynin

Question 14

Treatment of anaphylactoid reaction to N-acetylcysteine?

Answer 14

Stop infusion and restart at lower rate

Question 15

Peripheral blood smear showing RBC agglutination is indicative of what disease?

Answer 15

Mycoplasma pneumoniae

Question 16

What ABG can heroin overdose produce?

Answer 16

Resp depression > hypoventilation >

resp acidosis

Question 17

Oesophageal ulcers are probably caused by?

Answer 17

Alendronic acid

Question 18

Whooping cough treatment in kids?

Answer 18

Oral azithromycin

Question 19

Rifampicin SEs?

Answer 19

Hepatitis
Orange secretions
Flu-like symptoms

(Rifampicin is potent liver enzyme inducer)

Question 20

SEs of isoniazid?

Answer 20

Peripheral neuropathy
Hepatitis
Agranulocytosis

Liver enzyme inhibitor

Question 21

SEs of pyrazinamide?

Answer 21

Hyperuricaemia causing gout
Arthralgia, myalgia
Hepatitis

Question 22

SEs of ethambutol?

Answer 22

Optic neuritis

Question 23

Haematuria means what test is required?

Answer 23

MSU

Question 24

In pregnancy if patient has cellulitis and is penicillin allergic what do you want to prescribe her?

Answer 24

Erythromycin

Question 25

Life threatening C Diff treatment?

Answer 25

ORAL Vancomycin IV metronidazole

Question 26

Name of criteria for liver transplantation in paracetamol liver failure? + criteria

Answer 26

King's College Hospital Criteria Arterial pH <7.3, 24 hours after ingestion or all of following: - PT time >100secs -Creatinine >300umol/l -Grade III or IV encephalopathy

Question 27

Paediatric BLS: if no signs of breathing on initial assessment what do you do?

Answer 27

5 rescue breaths

Question 28

Continuous IECOPD treatment?

Answer 28

Azithro once-daily

Question 29

What artery bleed is most likely to cause leg weakness without face or speech impairment?

Answer 29

Anterior cerebral artery

Question 30

Compressions for kids rate?

Answer 30

100-120

Question 31

Where is this stroke? -Sudden onset vertigo and vomiting -Ipsilateral facial paralysis -Deafness

Answer 31

Anterior inferior cerebellar artery

Question 32

What type of diagnoses is this? Hypodense (dark) crescenteric collection around convexity of brain?

Answer 32

Chronic subdural haematoma

Question 33

Which conditions have postural hypotension with compensatory tachycardia?

Answer 33

4D's -Deconditioning -Dysfunctional heart: aortic stenosis -Dehydration, dialysis -Drugs: anti-anginals anti-psychotics, tamsulosin, anti-parkinsonian drugs

Question 34

Diagnosis of legionella

Answer 34

Urinary antigen test

Question 34

What lobe of brain causes lip smacking, epigastric aura etc?

Answer 34

Temporal lobe

Question 34

What do frontal lobe seizures present with?

Answer 34

Jacksonian march (paraesthesia distal peripheries proximally) Todd's paralysis

Question 35

Salicylate poisoning blood gases?

Answer 35

Resp alkalosis -> metabolic acidosis

Question 35

Contralateral homonymous hemianopia with macular sparing + visual agnosia?

Answer 35

Posterior cerebral artery stroke

Question 36

Where to check pulses in an infant?

Answer 36

Brachial or femoral

Question 37

Drugs to stop in AKI?

Answer 37

CANADA Contrast media ACEIs NSAIDs AMinoglycosides Diuretics ARBs

Question 38

Addison's disease blood gas?

Answer 38

Hyperkalaemic metabolic acidosis

Question 39

Common consequence of SAH?

Answer 39

SIADH

Question 40

What type of lesions is staph aureus pneumoniae assoc with?

Answer 40

Cavitating lesions

Question 41

SAH comp?

Answer 41

Hyponatraemia

Question 42

Prophylaxis of contacts of patient's who have meingococcal meningitis?

Answer 42

Oral rifampicin Oral ciprofloxacin