Cancer Flashcards
Treatment of chronic myeloid leukaemia?
Imatinib (Tyrosine Kinase Inhibitor)
What on a blood test could indicated lung cancer?
Raised platelets
SCLC + lef weakness makes you think what?
Lambert Eaton syndrome
HPV 6 & 11 bad or good?
Good (in relativity)
Only cause genital warts
Cancerous HPV types?
16 & 18
WHat type of cancer is schistosomiasis a RF for?
SCC of the bladder
Pancreatic cancer invgX?
High res CT
Blood film finding of CLL?
Smudge cells
The is a greater/lesser risk if ovulation is not suppressed for ovarian cancer?
Greater
-Early menarche
-Late menopause
-Obesity
-Hormone replacement therapy
What can NSAIDs increase the risk of in patients with chicken pox?
Nec Fasciitis
What illicit drug can increase risk of serotonin syndrome in SSRI users?
MDMA
What can be prevented by prescribing isoniazid and pyridoxine together?
Peripheral neuropathy
Urge incontinence treatment in elderly people to avoid them becoming confused?
Mirabegron instead of oxybutynin
Treatment of anaphylactoid reaction to N-acetylcysteine?
Stop infusion and restart at lower rate
Peripheral blood smear showing RBC agglutination is indicative of what disease?
Mycoplasma pneumoniae
What ABG can heroin overdose produce?
Resp depression > hypoventilation >
resp acidosis
Oesophageal ulcers are probably caused by?
Alendronic acid
Whooping cough treatment in kids?
Oral azithromycin
Rifampicin SEs?
Hepatitis
Orange secretions
Flu-like symptoms
(Rifampicin is potent liver enzyme inducer)
SEs of isoniazid?
Peripheral neuropathy
Hepatitis
Agranulocytosis
Liver enzyme inhibitor
SEs of pyrazinamide?
Hyperuricaemia causing gout
Arthralgia, myalgia
Hepatitis
SEs of ethambutol?
Optic neuritis
Haematuria means what test is required?
MSU
In pregnancy if patient has cellulitis and is penicillin allergic what do you want to prescribe her?
Erythromycin
Life threatening C Diff treatment?
ORAL Vancomycin
IV metronidazole
Name of criteria for liver transplantation in paracetamol liver failure? + criteria
King’s College Hospital Criteria
Arterial pH <7.3, 24 hours after ingestion
or all of following:
- PT time >100secs
-Creatinine >300umol/l
-Grade III or IV encephalopathy
Paediatric BLS: if no signs of breathing on initial assessment what do you do?
5 rescue breaths
Continuous IECOPD treatment?
Azithro once-daily
What artery bleed is most likely to cause leg weakness without face or speech impairment?
Anterior cerebral artery
Compressions for kids rate?
100-120
Where is this stroke?
-Sudden onset vertigo and vomiting
-Ipsilateral facial paralysis
-Deafness
Anterior inferior cerebellar artery
What type of diagnoses is this?
Hypodense (dark) crescenteric collection around convexity of brain?
Chronic subdural haematoma
Which conditions have postural hypotension with compensatory tachycardia?
4D’s
-Deconditioning
-Dysfunctional heart: aortic stenosis
-Dehydration, dialysis
-Drugs: anti-anginals anti-psychotics, tamsulosin, anti-parkinsonian drugs
Diagnosis of legionella
Urinary antigen test
What lobe of brain causes lip smacking, epigastric aura etc?
Temporal lobe
What do frontal lobe seizures present with?
Jacksonian march (paraesthesia distal peripheries proximally)
Todd’s paralysis
Salicylate poisoning blood gases?
Resp alkalosis -> metabolic acidosis
Contralateral homonymous hemianopia with macular sparing + visual agnosia?
Posterior cerebral artery stroke
Where to check pulses in an infant?
Brachial or femoral
Drugs to stop in AKI?
CANADA
Contrast media
ACEIs
NSAIDs
AMinoglycosides
Diuretics
ARBs
Addison’s disease blood gas?
Hyperkalaemic metabolic acidosis
Common consequence of SAH?
SIADH
What type of lesions is staph aureus pneumoniae assoc with?
Cavitating lesions
SAH comp?
Hyponatraemia
Prophylaxis of contacts of patient’s who have meingococcal meningitis?
Oral rifampicin
Oral ciprofloxacin
