Breast Flashcards
What determines management before surgery in breast cancer patients?
Presence/absence of axillary lymphadenopathy
-No palpable: pre-op axillary US before 1st surgery
-If that’s negative then sentinel node biopsy
If ptnt presents with breast cancer + palpable lymphadenopathy what is indicated?
Axillary node clearance
What hormonal therapy is used in pre/peri-menopausal women?
Tamoxifen
What hormonal treatment is used in post-menopausal women?
Aromatose inhibitor (anastrozole)
Anastrozole or letrozole is used for what category + of breast cancer?
ER +ve
What drug is used in HER2 +ve tumors?
Trastuzumab (Herceptin)
SE of axillary node clearance in Breast Canc?
Lymphoedema + functional arm impairment
What is tamoxifen used against?
Oestrogen receptor +ve breast cancers
Breast mice?
Fibroadenoma
(discrete, non-tender, mobile lumps)
Lumpy breasts?
Fibroadenosis
Nippley eczema?
Paget’s disease of breast
Obese woman, following trauma, firm round lump may become hard?
Fat necrosis
What size would you chop out a fibroadenoma?
3cm or more
1st line for cyclical mastalgia?
Supportive bra
Simple analgesia
Mechanism of anatrazole?
Inhibition of peripheral oestrogen synthesis