Calcium Homeostasis Flashcards

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1
Q

What hormones are used for mineral resorption

A

Parathyroid hormone (PHT) and Calcitriol (Vitamin D)

These hormones increase calcium levels in the blood, and mineral resorption is the process of breaking down bone to increase calcium in the blood

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2
Q

What hormones are used for mineral Deposition

A

Calcitonin

Calcitonin decreases calcium levels in the blood and mineral deposition is the process of taking calcium from bone and depositing it into bone

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3
Q

If I needed more calcium in my blood, what would my body do?

A

Undergo mineral resorption.

Use parathyroid hormone and calcitriol (vitamin D) to to dissolve bone releasing calcium from bone and increase the calcium levels into the blood

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4
Q

When blood calcium levels are too high, what happens to calcitonin?

A

Calcitonin is secreted by C cells in the thyroid gland

Inhibit osteoclasts (that break bone to produce more calcium for blood)

Stimulate osteoblasts (take calcium from blood and put it into bone)

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5
Q

What is the process of moving calcium from the blood into bone

A

Mineral deposition

The process were calcium, phosphate, and other ions are taken from the blood and deposited into bone

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6
Q

What is the process of dissolving bone and releasing minerals into the blood?

A

Mineral resorption

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7
Q

What is the function of the thyroid gland in regards to calcium homeostasis?

A

The thyroid gland produces calcitonin (when blood calcium levels are too high) which STIMULATES osteoblasts and the deposition of calcium into bones

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8
Q

What is the function of the parathyroid clans and relation to calcium homeostasis?

A

Produces parathyroid hormone (PTH)

Aiding in mineral Resorption by STIMULATING osteoclasts to break down bone to INCREASE blood calcium levels

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9
Q

When blood calcium is low, which hormones are our secreted?

A

Parathyroid hormone from parathyroid gland

calcitriol from vitamin d produced by skin

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10
Q

What effects does calcitonin have?

A

Lowers blood calcium

Inhibits osteoclasts

Produced by C cells in Thyroid glad when blood calcium is to high

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11
Q

What effects does calcitriol have?

A

Raises blood calcium level
Produced by epidermal cells

Increases calcium resorption from skeleton
Increases calcium absorption by small intestines
Increases calcium reabsorption in kidneys

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12
Q

What effect does parathyroid hormone have?

A

Raise blood calcium
Stimulate osteoclasts
Secreted by parathyroid glands when blood calcium is low

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13
Q

What is Hypocalcemia?

A

Deficient calcium in blood

causes overly excitable nervous system + tetany (muscle spasms)

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14
Q

What are the causes of Hypocalcemia

A

Vitamin D deficiency, Diarrhea, thyroid tumors, underactive parathyroid glands

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15
Q

What increases the risk of Hypocalcemia?

A

Pregnancy + lactation = higher risk

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16
Q

What are the symptoms of hypocalcemia?

A

Convulsions
Arrhythmias
Tetany
Stridor and spasms

17
Q

What is hypercalcemia

A

Excessive calcium levels

18
Q

What are the effects of hypercalcemia?

A

Increased calcium makes Ion channels less responsive. Thus nerve and muscles are less excitable.

19
Q

What can hypercalcemia lead to

A

Muscle weakness
Sluggish reflex
Cardiac arrest