C3 - Hymenolepiasis Flashcards
- A cosmopolitan disease encountered more frequently in tropics than in colder climates. - disease is acquiredbyingestion of eggs of H. nana or arthropods containing larval stages of H. diminuta.
Hymenolepiasis
causes hymenolepiasis
- Hymenolepis nana (dwarf tapeworm)
- Hymenolepis diminuta (rat tapeworm)
size of H. nana
15-40 mm
size of H. diminuta
20-60 cm
egg size of H. nana
30-50 micrometer
egg size of H. diminuta
60-85 micrometer
polar filaments of H. nana
4-8
polar filaments of H. diminuta
absent
outer membrane of H. nana
thin
outer membrane H. diminuta
thick
hooks in oncosphere of the two Hymenolepis sp.
6
life cycle of H. nana outside host
- egg in feces
- egg ingested by insect and develops into cysticercoid or
- embryonated egg ingested by humans from contaminated food, water, or hands
- humans and rodents infected when they ingested cysticercoid-infected arthropods
life cycle of H. nana inside host
- oncosphere hatches and cysticercoid develops in intestinal villus
- scolex is formed
- adult in ileal portion of small intestine
- eggs can be released through the genital atrium of the gravid proglottids. Gravid proglottids can also disintegrate, releasing eggs in stools
- autoinfection can occur and eggs release hexacanth embryo which penetrates intestinal villus, continuing the cycle
life span of H. nana egg
10 days
how long do adult H. nana reside in small intestine
4-6 weeks
life cycle of H. diminuta
- eggs passed out in feces
- eggs ingested by intermediate host
- oncosphere penetrates arthropod’s intestinal wall and develop into cysticercoid larvae
- mammals acquire infection by injesting cysticercoid larvae
- larvae evert their scolex to attach to intestinal wall
- parasites mature in small intestine
- eggs are released in feces
transmission of Hymenolepis
- consumption of infected insects
- fecal-oral route
symptoms of Hymenolepiasis
- usually asymptomatic
if symptomatic
1. nausea
2. weakness
3. loss of appetite
4. diarrhea
5. abdominal pain
6. anorexia
severe symptoms of hymenolepiasis
- headache
- itchy bottom
- difficulty sleeping
diagnosis for hymenolepiasis
tool sample examination
- should be repeated one month after therapy
geographical distribution of hymenolepis
- worldwide
- common in warm climates
- (Europe, asia, africa, americas)
who is at risk of hymenolepiasis
- children
- people living in institutional settings
- areas with unimproved sanitation facilities
treatment of hymenolepiasis
- praziquantel
- nitazoxanide
- nicloxamide
- dissolve tapeworm in the intestine
prevention for hymenolepiasis
- hand washing
- sanitary preparation of food