Bullous Pemphigoid Flashcards by Rusna Dhanjal | Brainscape

Q

What is Bullous Pemphigoid?

A

Auto-immune condition causing sub-epidermal blistering of the skin
Secondary to the development of antibodies against hemidesmosomal proteins BP180 and BP230

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Q

What are the features of Bullous Pemphigoid?

A

Itchy, tense blisters typically around the flexures
Blisters usually heal without scarring
There is stereotypically no muscosal involvement

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Q

What investigations would you do ?

A

Skin Biopsy: immunofluorescence shows IgG and C3 dermoepidermal junction

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