breast tx

Question 1

tamoxifen mechanism of action and use

Answer 1

ostrogen receptor antagonist- eostrogen sensitive breast cancer, mainly for premanopausal

Question 2

anastrozole mechanism of ation and use

Answer 2

aromatase inhibtor (inhibits the conversion of androgens into oestrogen) for post menaopausal patients with oestrogen receptor- positive breast cancer

Question 3

Trastuzumab mechanism of action and use

Answer 3

monoclonal antibody- HER2 positive patients, either as neoadjuvant therapy to downstage the tumour or as part of the overall treatment regimen.

Question 4

pagets disease of the nipple tx

Answer 4

primarily surgical.

simple mastectomy/modified radical mastectomy (removes axillary nodes too)
breast conserving surgery- for small cancers

Question 5

fat necrosis tx

Answer 5

reassurance. may need observation in case inc in s9ize etc.

Question 6

fibroadenoma tx

Answer 6

nil usually
if large, growing, causing sig.fig. symptoms or diagnostic uncertainty- excise.

Question 7

mastitis antibitoic tx

Answer 7

flucox TEN DAYS