Brain: food perception and regulation Flashcards

1
Q

what does the cerebellum do

A

integrating sensory perception

process brain responses - emotional regulation, cognitive and sensory perception - visual memory sound

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2
Q

what is the largest structure in the brain

A

cerebellum

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3
Q

where is the brain stem

A

connects spinal cord to brain

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4
Q

which are the areas in the neurone structure

A

darker - cell body

light - myelin sheath, axon

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5
Q

what happens when food is eaten - sensory

A

senses transported from receptors

transmitted then projected to primary sensory areas in brain

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6
Q

what happens when taste is detected

A

detected on taste buds
signals transmitted through taste fibres to brain stem
protected to thalamus
projected then to primary taste cortex

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7
Q

what happens when sight of food detected

A

detected by eye receptors then to thalamus

transmitted into visual cortex

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8
Q

what is the thalamus

A

gateway to primary sensory areas

ALL EXCEPT OLFACTORY pass through thalamus

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9
Q

how is the brains reward circuitry activated

A

eating
food anticipation
partly mediated by dopamine

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10
Q

where is dopamine released from

A

VTA then projected to other areas in brain where dopamine receptors are

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11
Q

where are the dopamine receptors

A

hippocampus
amygdala
nucleus accumbens
prefrontal cortex

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12
Q

what is the hippocampus involved in

A

forming memory

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13
Q

what is the amygdala involved in

A

emotion

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14
Q

what is the nucleus accumbens involved in

A

positive motivation

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15
Q

what is the prefrontal cortex involved in

A

cognitive and attention

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16
Q

what occurs at the hypothalamus

A

metabolism integration - control appetite
receive neural and hormonal inputs from peripheral and central signalling
lots of communication between gut, stomach, brain - when to eat/stop

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17
Q

what is the hypothalamus made up of

A

subdivided into several nuclei (neruones)

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18
Q

what does the hypothalamus regulate

A

food balance in the body

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19
Q

where is the hypothalamus

A

below the thalamus

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20
Q

what is the ARC

A

arcuate nucleus

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21
Q

what is the LHA

A

lateral hypothalamic area

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22
Q

what is the VMN

A

ventromedial hypothalamic nucleus

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23
Q

what is the PVN

A

paraventricular nucleus

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24
Q

what is the DMN

A

dorsomedial hypothalamic nucleus

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25
what happens if the LHA is damaged
decrease in eating
26
what happens if the VMN is damaged
increase in eating
27
what are the two main forms of carbohyrdates
starch | sugar
28
what provides the brain with energy
glucose can be used directly
29
what is the effect that different sugars have on the brain
different impacts
30
where is glucose stored and how is it delivered
neurons can't store glucose | depend on bloodstream to deliver constant supply
31
what is a good diet for supplying the brain with long-time glucose, improve memory and coginition
fibre-rich
32
what makes up most of the brains dry weight
fatty acids 60%
33
how are fatty acids involved in the brain
involved in brains development, growth | affect cognitive abilities
34
how is the neuronal function altered by food intake
fats alter nerve cell membrane and myeline sheath composition
35
how much of the body is protein
20%
36
what does protein rich food cause - hormones and their cause
increases - dopamine - norepinephrine affect reward, pleasure, motivation
37
how is the brain studied
MRI is non-invasive
38
how does MRI scan work
MRI relies on hydrogen atoms for picture of body (body 70% water) hydrogen atoms create a magnetic field
39
what are the hydrogen atoms like when outside scanner
randomly aligned
40
what are the hydrogen atoms like inside the scanner
aligned parallel to be in line with magnetic field
41
what are the hydrogen atoms like when the RF pulse is applied
sends energy to protons, they change direction due to absorbed energy causes them to be perpendicular to magnetic field
42
what are the hydrogen atoms like when the RF pulse is off
proton want to go back to original state emits energy absorbed - detected by MRI scanner form high-resolution picture
43
what is a haemodynamic response
stimulus, neurones fire signals cause rapid increase in neuronal activity vesicles dilate, allow blood flow for more oxygenation
44
what is the indirect measure of brain activity
haemodynamic response
45
what is the direct measure of brain activity
measure electrical activity generated from neurones
46
what is MEG and what does it do
measures magnetic field generated from electrical activity - direct measuring
47
what is EEG
measure electric activity of brain
48
when does the brain consume more energy
when the neurones are activate
49
what is fMRI
functional magnetic resonance imaging
50
what does fMRI do
relies on oxygenated and deoxygenated blood as they have different levels of magnetic properties can be detected by MRI scanner
51
when at rest what happens in fMRI - oxygen ratios - MRI shows
ratio of oxygenated : deoxygenated similar | MRI silent
52
during activation what happens in fMRI
oxygen consumed so oxygenated blood increases | increases MRI signal
53
what is BOLD
blood oxygen level dependent
54
how can we see when brain responds to taste perception
compare brain response during activation and rest
55
what is PET
positron emission tomography
56
what does PET do
observe metabolic processes in body | measures glucose metabolism following neurone activity
57
why may fat be considered as a sense
oral fat activated, taste and somatosensory | causes brain responses
58
what happens after high fat meal consumed
increase cholecystokinin plasma
59
what happens after a high water content meal consumed
after 30 minutes CCK level higher, even higher after 80min
60
what is CBF
cerebral blood flow
61
what happens to CBF after a fat meal | what area of brain is affected
CBF decreases | satiety brain areas
62
what happens to CBF after water meal | what area of the brain is affected
CBF increased | reward areas
63
what happens when high calorie food consumed
high reward - significant activation in brain reward centre
64
what happens when low calorie food consumed
lead to activation in somatosensory areas but no activation in brain reward centre
65
what is the effect of body weight on brain response
obese have higher brain response to taste and hedonic areas
66
what is the effect of omega-3 on brain structure
increased grey matter - memory emotion and cognition areas