Bovine Urology Flashcards
What should you look for in the urethral area of males?
Hematomas
Ruptured urethra
“Water belly”
Ruptured urethra
In what animals would you use Radiography in urology?
Young and small ruminants
Cow Micturition
Usually urinate right after standing
Arched back, raised tail, straddled legs
May urinate when eating, walking, or lying down
Bull Micturition
Arched back, raised tail
may dribble urine or urinate with repeated short pulsations
How do you collect urine in cows?
Stimulate vulva or catheterize (“feather”)
How do you collect urine in the bull?
Preputial massage
Catheterization too difficult
How do you collect urine in a ewe?
Hold of nose
Why can you not catheterize a bull or steer?
Sigmoid flexure
How many times a day do sheep and goats urinate?
1-3/day
How many times a day do cattle urinate?
5-6/day
How many times a day do swine urinate?
2-3/day
How much do sheep and goats urinate per day?
10-40ml/kg
How much do Cattle urinate per day?
17-45ml/kg
How much do swine urinate per day?
5-30ml/kg
Where is the left kidney located?
3rd-5th lumbar vertebra
Where is the right kidney located?
12th thoracic - 3rd lumbar vertebra
Describe the kidney n the bovine
Lobulated
Describe normal urine characteristics
Water viscosity
Straw or amber colored
Clear, transparent
pH 7-8
What is the normal specific gravity of cows?
1.020-1.040
What are the differentials of Hematuria?
Pyelonephritis cystitis urolithiasis enzootic hematuria embolic nephritis
What are the differentials of Hemoglobinuria?
Leptospirosis Bacillary hemoglobinuria copper toxicity post-parturient hemoglobinuria cold water intoxication
What are the differentials of Myoglobinuria?
Cassia toxicity
capture myopathy
Describe BUN and CREA relationship in bovine urine
Creatinine may increase more quickly than BUN due to the ruminant’s ability to recycle urea through the rumen
What is common in small ruminants?
Obstructive urolithiasis
What are the predisposing factors for Obstructive urolithiasis?
Castrated males with decreased diameter of urethra increased urine concentration urine stasis increased urine pH increase mineral excretion decreased urinary colloids desquamated epithelial cells UT infections Increased urinary mucoproteins
What are the dietary influences involved with Struvite and/or calcium phosphate obstructive urolithiasis?
High concentrate diets Diets high in calcium, magnesium, and/or phosphorus Low Calcium Phosphorus ratio Pelleted rations Vitamin A deficiency
What are the dietary influences involved with Calcium carbonate and/or calcium oxalate obstructive urolithiasis?
Legumes
Apples
Sweet potatoes
Dock Pigweed
What kind of urine do most calculi form in?
alkaline
What factors favor development of obstruction?
Long convoluted urethra
sigmoid flexure
Early castration
Exogenous estrogens
What exogenous estrogens can contribute to obstruction?
Clover
Feedlot cattle with implants
What are the common sites for obstruction in the urinary tract?
Urethral process
Distal sigmoid flexure
Struvite
Magnesium ammonium phosphate
Apatite
Calcium phosphate
What does prolonged partial obstruction cause?
Hydroureter
Hydronephrosis
Bladder wall damage
Urethral strictures
Clinical signs of Obstructive urolithiasis
Stranguria Urethral pulsations without urination Anorexia Mild bloat Kicking @ abdomen Tail switching Vocalization Palpable bladder distention Azotemia
What are the clinical findings of obstructive urolithiasis?
Blood or crystals on preputial hairs Mild urethral swelling at site of obstruction Preputial/rectal prolapse Tachypnea Tachycardia Metabolic abnormalities
What are the clinical findings for obstructive urolithiasis?
Elevated creatinine Hyponatremia Hypochloremia Hyperkalemia Creatinine of abdominal or SQ fluid 1.5-2 times serum
What is the sequelae to untreated obstruction?
Ruptured urethra with accumulation of SQ urine ventrally
Ruptured bladder with development of uroperitoneum
Subcutaneous urine accumulation leads to necrosis and skin slough if not drained
What are the clinical signs of ruptured urethra?
Ventral and preputial edema
Aspirated fluid smells like urine when heated
Signs of uremia
Preputial adhesions
in Chronic cases, skin and SQ tissues begin to slough
Clinical signs of Ruptured bladder
Pain may subside Gradual abdominal distension Depression and anorexia Signs of uremia Large amounts of abdominal fluid with abdominal ultrasonography Clear fluid on abdominal tap
What is the medical treatment for obstructive urolithiasis?
Phenothiazine tranquilizers IV fluids - 0.9% NaCl Slow drainage of uroperitoneum via trochar Paramedian skin incision to drain urine Antibiotics Urinary acidifiers
What is the surgical management for obstructive urolithiasis?
Amputation of urethral process Urethral catheterization/ retrograde flushing Perineal urethrostomy Tube cystotomy Ischial urethrostomy Cystostomy
What is the treatment of urethral obstruction?
Antispasmodics: Acepromazine
Urethral catheterization
Urethral Bladder lavage
What is the surgical treatment for Urethral obstruction in animals bound for slaughter?
Urethrostomy
Penile Amputation
Urethrotomy
What is the surgical treatment for obstructive urolithiasis in breeding animals and pets?
Tube cystostomy
Bladder marsupialization
What is a useful surgical treatment for obstructive urolithiamsis in small ruminants and calves?
Tube cystotomy
What is the advantage of Urinary Bladder marsupialization?
long term resolution of urinary obstruction in small ruminants not intended for slaughter
What is a complication of Urinary Bladder marsupialization
Urine Scald
How do you treat Urethral Rupture?
Urethrostomy
Penile Amputation
Tube cystostomy
How do you treat Ruptured bladder?
Tube cystostomy for breeding animals and pets
Urethrostomy with catheterization to allow bladder to heal
What is a salvage procedure of the urinary system?
Perineal urethrostomy
How do you prevent obstructive urolithiasis?
Delay castration Recommend female pets Increased water uptake Avoid grain supplements in pets Avoid legume hay Avoid excess protein Urinary acidifiers: Ammonium chloride
What causes ascending urinary tract infections?
Stagnation of urine flow from dehydration Downer cows Infected urachus Cystotomy tubes Trauma from uroliths
What causes Pyelonephritis?
Opportunistic/environmental pathogens
Infectious pathogens
Clinical signs of UTI/Pyelonephritis
Ill thrift Fever Vague colic signs Stranguria Purulent material or blood in urine
What is the treatment for UTI/Pyelonephritis?
Culture and sensitivity
Penicillins and Beta-lactams
Promoting diuresis
What causes Contagious Bovine Pyelonephritis?
Corynebacterium renale
What are the clinical signs of Contagious Bovine Pyelonephritis?
Hematuria Pollakiuria pyuria Thickened bladder wall enlarged ureters painful kidney RBCs, WBCs, protein, and bacteria in UA
Treatment for Contagious Bovine Pyelonephritis?
Penicillin for 2 weeks
Nephrectomy
Ulcerative Posthitis and vulvitis
C. renale hydrolyzes urea to form ammonia in urine of animals on high protein diet which excreting high level of urea in long haired animals causing swelling + preputial prolapse or ulcers and distort vuvlar commisure
What is the treatment for Ulcerative posthitis and vulvitis?
Debride and emollient antibacterial ointment
Dry environment
Penicillin
Reduce protein in the diet
Petercillin: Lanolin + Scarlet Oil + Oxytetracycline
What agent causes Necrotic Posthitis?
Fusobacterium necrophorum
Necrotic Posthitis
Necrosis of the prepuce usually in wet feedlot pens from Fusobacterium necrophorum
What is the treatment for Necrotic Posthitis?
Debride and emollient antibacterial ointment
Dry environment
Penicillin
“Thin sow syndrome”
Corynebacterium suis causing cystitis and pyelonephritis
How is Corynebacterium suis transmitted?
Venereal
What is the treatment of Corynebacterium suis?
Penicillin
What does Leptospirosis Pomona cause?
severe hemolytic disease
interstitial nephritis
tubular necrosis in calves
What does Leptospirosis grippotyphosa cause?
severe hemolytic disease
interstitial nephritis
tubular necrosis in calves
How do you diagnose Lepto?
Microscopic agglutination test Phase contract microscopy dark-field microscopy immunofluorescent antibody test PCR
Lepto Treatment
Tetracyclines
Penicillins
How do you prevent Lepto?
Vaccination
Remove access to standing water
Embolic nephritis
Bacteria lodge in small vessels/ create infarcts in kidney
Treat with antibiotics
What are the Nephrotoxic metal agents?
Arsenic Mercury Lead Zinc Copper
What are the Antimicrobial Nephrotoxic agents?
Aminoglycosides Tetracyclines Sulfonamides Ionophores NSAIDs
What are the Nephrotoxic plants?
Amaranthus retroflexus
Lilium
Quercus
Xanthium
What are the Nephrotoxic agents?
Ethylene glycol
Vitamin C overdose
Vitamin D overdose
Mycotoxin
What does Amaranthus retroflexus cause?
Perirenal edema and kidney pathology
Death due to hyperkalemia
What causes Bovine Enzootic Hematuria?
Bracken fern
What does Bracken fern cause?
intermittent hematuria
bladder neoplasia = transitional cell carcinoma
What does Oak poisoning cause?
Hepatotoxic nephrotoxic precipitation of proteins gastroenteritis hemorrhages edema renal lesions
What are the toxic principles of Oak poisoning?
Tannin
Gallotanin
What are the clincal signs of Renal amyloidosis?
Hypoproteinemia
Proteinuria
edema
diarrhea
What is the treatment of Renal amyloidosis?
No treatment
What are the congenital defects of the urinary system?
Patent urachus
Urachal abscess
Polycystic kidney
Renal oxalosis
When does Patent urachus occur?
following C-section
What are the common causes of Urachal abscess?
A. pyogenes
E. coli
Strep spp
Staphylococcus spp
What is the treatment for Urachal abscess?
Surgical resection
Polycystic kidney
enlarged kidneys with large cysts or several small cysts
What happens if polycystic kidney is unilateral?
other kidney compensates
What happens if polycystic kidney is bilateral?
calves are usually stillborn or die shortly after birth
Renal oxalosis
Cows exposed to excess oxalate levels deposits in fetal glomeruli, tubules & collecting ducts
Neonates also usually have cardiac and/or musculoskeletal defects as well
What are the clinical signs of Urachal vestiges?
dysuria
pollakiuria
stranguria
What neoplasia is common in the external genitalia?
Fibropapilloma
Squamous cell carcinoma
What neoplasia is common in the kidney?
Lymphosarcoma
Adenoma
Nephroblastoma
What neoplasia is common in the bladder?
Transitional cell carcinoma