Bovine GI Flashcards
What do old cows living in a sandy area die from?
Dental Attrition
Cleft palate
palate closes from rostral to caudal, defect is always in back. Milk comes out of nose when head is down.
In what breed is Cleft palate inherited?
Charolais
What causes pitting of teeth?
Fluorosis, weak teeth
What causes fluorosis?
Areas with a lot of factories. High levels of fluoride get into the air and then into the soil and the grass.
How do you diagnose Fluorosis?
by removing bone from tail and have it analyzed
Brachygnathia
Short mandible or a “weak jaw”
Adamantonoma
tumor of the teeth
What is the treatment for Adamantonoma?
Culling
Ptyalism
Excessive salivation
DDx for Ptyalism
choke ruminal and abomasal problems toxicities rabies side effects of xylazine
Sialadenitis
Inflammation of the salivary gland
How do you treat Sialadenitis?
Reduce swelling
Drain abscess
broad spectrum Abx
Wounds and infections of glands usually heal by second intention
What can a Sialadenitis lead to?
Salivary cyst
Salivary gland neoplasia
Pleomorphic carcinomas
Squamous cell carcinoma
What is the cause for Trauma/Abscess?
Iatrogenic
Frick Spectrum
Balling gun
What are the clinical signs of Trauma/Abscess?
Anorexia depression Coughing dyspnea Painful swallowing
What is the treatment for Trauma/Abscess?
Drainage of Abscess to outside or drain into esophagus to be swallowed
Antibiotics
Actinobacillus
“Woody Tongue”
Affects the soft tissues causing painful, nodular lesions involving the soft tissues such as the tongue, lips, nose, infection in oral cavity leading to swelling at base of tongue, difficulty eating
How do you diagnose Actinobacillosis?
Examine pus - sulfur granules and gram negative rod shaped bacteria
What is the treatment for Actinobacillosis?
Surgical debridement and flushing wwith iodine solution
Potassium iodide orally or sodium iodide IV
Oxytetracycline or tilmicosin
Actinomycosis
“Lumpy jaw”
Affects the bone tissue usually in the mandible causing lesions to develop in the mandible or maxilla or the soft tissue after entering through oral abrasion usually a hard, immovable mass and fistulous tract
If the teeth become involved with Actinomycosis what is the treatment?
Culling
How do you diagnose Actinomycosis?
Gram positive filamentous branching organism with sulfur granules
What is the treatment for Actinomycosis?
Sodium Iodide IV once a week for several weeks
Surgical drainage of bone, abscess followed by flushing or packing with iodine
Lugol’s solution - potassium iodide plue iodine given parenterally
Radiation therapy
What is the most common treatment for Actinomycosis?
Culling
What causes Choke?
Ingestion of foreign objects
Greedy eating, dry roughages, Apples, Potatoes
What are the clinical signs of Choke?
Anxiety
salivation
coughing
bloat
How do you diagnose Choke?
PE
History
think rabies
inability to pass gastric tube
What are the primary locations for esophageal blockage?
Pharyngeal inlet #1
thoracic inlet
Base of the heart
Cardia of the rumen
Stomatitis
Inflammation of oral cavity
What are the primary causes of Stomatitis?
Trauma Plant awns Foreign bodies Malocclusion of teeth Chemical
What is Stomatitis secondary to?
Bovine papular Wooden tongue Foot and mouth Malignant catarrhal fever BVD Bluetongue
What is important to remember about Vesicular Stomatitis?
Reportable Disease
Can affect horses
Clinical signs of Vesicular Stomatitis
Formation of vesicles containing clear or yellow serous fluid
Ulcerations of the mouth, teats, and interdigital areas
How is vesicular stomatitis spread?
Poor milking hygiene
Insects
What causes Vesicular Stomatitis?
Rhabdovirus
What causes Bovine Papular Stomatitis?
Parapoxvirus
Clinical signs of Bovine Papular Stomatitis
Raised reddish papules on lips, muzzle, oral mucosa, head palate or inside nostrils
What is important to know about Bovine Papular Stomatitis?
can cause painful proliferative lesions in humans
What is the treatment for Bovine Papular Stomatitis?
Palliative treatment
Soft foods or gastric tube feeding
self limiting
What causes Traumatic Reticuloperitonitis?
Foreign object penetration of the reticulum resulting in localized or generalized peritonitis
Can penetrate the pericardium
Where is the common site for Traumatic Reticuloperitonitis?
Right medial wall of the reticulum
What is the treatment for Traumatic Reticuloperitonitis?
Magnet
What are some sequelae to Traumatic Reticuloperitonitis?
Diaphragmatic hernia Acute pericarditis Rupture of left gastroepiploic artery Abscesses of the spleen, hepatic, diaphragmatic and pleura Pneumonia Endocarditis Arthritis Nephritis Rupture of coronary artery or ventricular wall cardiac tamponade
What are the clinical signs of Traumatic Reticuloperitonitis?
Fever Anorexia Depressed decreased or absent rumen contractions Cranial abdominal pain Reluctant to move or lay down Expiratory grunt arched back stance
What is the most common type of Bovine Viral Diarrhea?
Non-cytopathic
What are the two types of Bovine Viral Diarrhea?
Cytopathic
Non-cytopathic
What is required for Mucosal Bovine viral Diarrhea to develop?
Cytopathic and Non-cytopathic
How is Bovine Viral Diarrhea transmitted?
Direct or Indirect
Transplacentally
What are the acute signs of Type 2 Bovine Viral Diarrhea?
Thrombocytopenia and hemorrhage High fever Anorexia and depression Abortions death
What does the outcome of infection in a pregnant animal depend on?
Strain of BVD
Stage of gestation
Immune status of cow
What is the outcome of infection with BVD during the 1st and 2nd trimester?
fetal death or abortion
What is the outcome of infection with BVD during 40-120 days of gestation?
Persistently infected
What are the characteristics of a persistently infected calf?
Animal is viremic when born
poor doer and will die within 1 year
mucosal disease if the PI animal becomes infected with a cytopathic strain
What is the outcome of BVD infection at 120-180 days of gestation?
Cerebellar hyperplasia
How do you diagnose BVDV?
Serology
ELISA
Fluorescent antibody test on nose/eye secretions
How do you control BVD?
Testing and elimination of PI animals
Can be spread in frozen semen (AI) or spread iatrogenically
Vaccination
What toxin affects the liver and causes livestock loss worldwide?
Pyrrolizidine alkaloids
How do Pyrrolizidine alkaloids damage the liver?
causes megalocytes and cellular death leading to fibrosis
When do you see the clinical signs of Pyrrolizidine alkaloid toxicosis?
1-5 months after ingestion
What are the clinical signs of Pyrrolizidine alkaloid toxicosis?
Ill thrift Anorexia Depression Diarrhea Ascites Seondary Photo sensitization Hepatoencephalopathy Coma death
How do you diagnose Pyrrolizidine alkaloid toxicosis?
Feed analysis
Liver biopsy
Tansy Ragwort
Animals eating 5% or more of daily diet for periods exceeding 20 days will die
Where do Aflatoxins com from?
Fungi on corn, peanuts, or cotton seed
What do aflatoxins cause?
liver damage
hepatic failure
What Mycotoxins can affect cattle?
Aflatoxins
Phomopsins
Sporidesmin
What plant is Sporidesmin associated with?
Rye grass
What are the clinical signs of copper toxicosis in cattle?
Intravenous hemolysis
depression
inappetance
What causes release of copper from the hepatocytes?
Stress
What causes iron induced liver failure?
overdose in calves
What is the pathophysiology of Blue green algae toxicosis?
Hepatotoxic cyclic peptides lead to disintegration of hepatocellular cytoskeleton
Death within one hour
Cocklebur
glycoside toxin carboxyatractyloside causes severe hypoglycemia and massive hepatic necrosis
What are the clinical signs of Cocklebur?
Depression dyspnea Weakness convulsions with opisthotonus sudden death
Cycads
glycoside cycasin causes cirrhosis, ascites, and hemorrhagic gastroenteritis
Lantana
Contains triterpenoid compounds causing intrahepatic cholestasis
What are the clinical signs of Lantana?
Anorexia
Dehydrated icteric
rumen stasis
photo sensitization
What causes Bacillary Hemoglobinuria?
Clostridium hemolyticum type D
What are the clinical signs of Bacillary Hemoglobinuria?
Port wine colored urine
liver necrosis
What is the treatment for Bacillary Hemoglobinuria?
Antibiotics
How do you control Bacillary Hemoglobinuria?
Vaccination
Fluke Treatment
What causes Black Disease?
Clostridium novyi
Immature liver fluke
Cattle grazing on irrigated pastures
What are the clinical signs of Black Disease?
Sudden death
Fever
toxemia
What bacteria causes liver abscesses?
Fusobacterium necrophorum
Corynebacterium
SARA
What are the clinical signs of Liver abscesses?
decreased weight gain
increased loss of weight
decreased milk production
What causes liver asbcesses?
Rumenitis diets high in carbs or grain overload
Ulceration in cranial sack of rumen
Bacterial emboli
Hemorrhagic Bowel Syndrome - “Bloody gut”
Sporadic frequently fatal enteric disease of adult dairy cattle
Seen during the first 3-4 months of lactation
Clinical signs of Hemorrhagic Bowel Syndrome?
massive hemorrhage into the small intestine with subsequent intraluminal formation of large clot and casts of blood that create intestinal obstruction
What may be the cause of Hemorrhagic Bowel Syndrome?
Clostridium perfringens Type A
Salmonella
BVDV
Aspergillus
How do you prevent Blood Gut?
Vaccination - C. perfringens Type A toxoid, Type C and D vaccine
What is the most common condition of mature high producing Cows?
Fatty liver
When do you usually see fatty liver in cows?
1-2 weeks post calving
What is the cause of fatty liver in cows?
Negative energy balance
Periparturient depression of feed intake contributes
Post partum metritis or mastitis
lipid accumulation triggered by increasing serum NEFA concentration
What are the clinical signs of Fatty Liver in cows?
Depression
anorexia
ketonuria
death in 7-10 days
How quickly does Fatty liver happen?
Within 48 hours
What causes Johne’s disease?
Mycobacterium avium paratuberculosis
How is Johne’s disease transmitted?
Ingestion - contaminated mil, water or feed
Shed in milk and colostrum
Intrauterine
What tissue is the target for Johne’s disease?
GI tract- Peyer’s patches in the Ileum
What are the clinical signs of Johne’s disease?
PLE leading to bottlejaw
persistent diarrhea
weight loss with good appetite
what is the age for animals with Johne’s disease?
3-5 years
what is an iceberg disease?
a disease that is indicative of bigger problems
How long does it take to eliminate Johne’s Disease from a herd?
7-20 years
How do you diagnose Johne’s Disease?
culture and isolation PCR Antibody (blood or milk) test ELISA AGID
How do you control Johne’s Disease?
cull
ELISA
Biosecurity
raise calves separately from adults
what is the common disease of livestock?
Salmonellosis
How is Salmonella transmitted?
Fecal-oral
What causes an animal to suffer from Salmonellosis?
immunosuppression
stress
dietary changes causing SARA
What is the most common form of Salmonella in calves?
Peracute
What are the clinical signs of Peracute Salmonellosis?
Fever depression dehydration diarrhea abdominal pain yellow feces with blood
What are the clinical signs for Acute Salomellosis?
Bloody Diarrhea
fever
What are the clinical signs off Chronic Salmonellosis?
Abortion
mastitis
Fever
water diarrhea
How do you control Salmonella?
Sanitation
Chlorinate water supply
Vaccination
What is the treatment for Salmonella?
Fluids and electrolytes
NSAIDs
Antimicrobials
Clean environment
What is the most common bacteria found in the environment?
E. Coli
What are the clinical signs of E.coli?
severe watery Diarrhea
dehydration