Bovine Respiratory Flashcards
What are the clinical signs of Sinusitis?
Obvious discharge from the head with or without facial deformities
Squint their eyes
hold their heads in unusual positions
press their heads against immovable objects
reluctant when the examiner approaches their head
Clinical signs of Nasal obstruction?
Unilateral airflow deficit
respiratory stridor
severe dyspnea with open mouth breathing due to bilateral obstruction
What causes Fungal granulomas or masses?
Actinoballilosis
Nocardiosis
What is the treatment for fungal masses?
Sodium Iodide IV q 10-14 days until resolves
What is the most common causes of Pharyngeal/Retropharyngeal Abscesses?
Inappropriate use of oral dosing equipment, stomach tubes, or potentially course feedstuffs
What are the clinical signs of Pharyngeal/Retropharyngeal Abscesses?
Head/neck extension excessive salivation Pharyngeal swelling Increased water or decreased feed malodorous breath with severe pain on palpation
What is the treatment for Pharyngeal/Retropharyngeal Abscesses?
Lancing the abscess
Tracheotomy
Antibiotics: Penicillins, oxytetracycline, florfenicol or ceftiofur
What occurs secondary to chondritis of the laryngeal cartilages?
Laryngeal/Pharyngeal Dysfunction
What causes Calf diptheria?
Fusobacterium necrophorum
What are the common names for Bovine Herpes Virus 1?
Infectious Bovine Rhinotracheitis
Red Nose
What systems are affected by BHV1.1?
Respiratory dz and abortion
What systems are affected by BHV1.2a?
genital tract infectious (vulvovaginitis)
What systems are affected by BHV1.2b?
respiratory dz but not abortion
What is the signalment for BHV1?
calves 6 months or older
How do you diagnose BHV1?
Nasal swabs immunofluorescence PCR ELIZA IHC
What happens with the infection of BHV1?
secondary infection with M. haemolytica, P. multocida, H. somni, or Mycoplasma spp.
What are the clinical signs for BHV1?
Fever Rhinitis Conjunctivitis Inappetance Labored breathing Drop in milk production Hyperemia of muzzle Pustules and diptheritic plaques ulceration of nasal mucosa and trachea
What cells are affect by Bovine Parainfluenza 3?
epithelial cells of the upper respiratory tract and alveoli
What is the result of Bovine Parainfluenza 3?
bronchitis
bronchiolitis
What are the clinical signs of Bovine Parainfluenza 3?
Fever (104-107) Depression Anorexia Nasal and ocular discharge Tracheal rales
What is important about Bovine Adenovirus?
Found in the respiratory tract and GI tract of inapparently sick and diseased animals
What is included in Bovine Respiratory Disease Complex?
Bovine Coronavirus
BRSV
BVDV
PI-3
What are the clinical signs of BRSV?
Fever causing abortion
What is the signalment of BRSV?
3-12 month old calves
What happens to the animal if it gets BRSV twice?
It dies
How is BRSV spread?
respiratory secretions
What cells are infected by BRSV?
epithelial cells of the nasal mucosa to the bronchi including type II pneumocytes and macrophages
What are the clinical signs of BRSV?
Fever (104-108)
+/- cough
Nasal and ocular discharge
pneumothorax from labored breathing
How do you diagnose BRSV?
Viral isolation from nasal swabs
PCR
IHC
How do you prevent BRSV?
Killed and MLV vaccines
What viruses are the in Pestivirus genus?
BVDV
Classical swine fever/hog cholera
border disease in sheep
What is the most important reservoir for BVDV?
persistently infected cattle
What is the most common form of BVD?
Non-cytopathic
What is the cause of perisistently infected cattle?
pregnant cattle becoming infected between 42 and 125 days
How is BVDV transmitted?
direct or close contact with infected cattle
Iatrogenic transmission
PI CATTLE!!
What organs are affected by BVDV?
Lymphoid organs
Mucosal disease of BVDV
a PI calf infected with the Non-cytotoxic strain becomes infected with the cytotoxic strain
How do you diagnose BVDV?
Virus isolation from nasal swabs
ELISA
Serology
What is the important part of preventing BVDV?
Biosecurity
Vaccination
What is the treatment for PI calves?
Euthanized
Fed to market weight
Shipping Fever
several factors that disrupt the innate immunity and mucociliary apparatus of the host allowing commensals to overgrow
What is the first lobe to be infected in cows with bacterial pneumonia?
Right Tracheal Bronchial Lobe
What is one of the most important pathogens of domestic cattle?
Manheimia haemolytica
What is the primary bacterial agent responsible for bovine pneumonic pasteurellosis?
Manheimia haemolytica
What is the route of transmission for Manheimia haemolytica?
Inhalation of bacteria containing droplets
Direct nose to nose contact
ingestion of feed contaminated with nasal discharges
What are the clinical signs associated with Manheimia haemolytica?
DART D - Depression A - Anorexia R - Respiration T - Temperature (Fever) Cough
What does Mannheimia haemolytica cause?
Severe fibrinous pleuropneumonia
“Hepatization” of the lung
What is the second most common pathogen associated with Shipping fever?
Pasteurella multocida
What is important about Pasteurella multocida?
Zoonotic
What does Pasteurella multocida cause?
Fibrinopurulent bronchopneumonia
Abscesses are common
What type of antibiotic can treat Pasteurella multocida?
Gram negative spectrum antibiotic
How is Histophilus somni transmitted?
Direct contact
Where does Histophilus somni colonize?
mucosal surfaces
What is a clinical sign of Histophilus somni?
Honking cough
Where do you find Histophilus somni survive?
Intracellularly in macrophages and neutrophils
What does Mycoplasma spp cause?
Lobar suppurative bronchopneumonia with severe peribronchial cuffing
pleuritis
Coagulative necrosis lesions of the bronchiole
What causes “pneumonia-arthritis syndrome”?
Mycoplasma bovis
What is important to know about Mycoplasma bovis vaccination?
vaccination results in high interferon gamma and Th-1 biased immune response with enhanced lung damage
What is a clinical sign of M. bovis in calves?
Cachexia
What is the method of choice for M. bovis diagnosis?
IHC
How do you treat M. bovis?
Resflor
Nuflor
Draxxin
Baytril
What causes ABPE (Fog Fever)?
1-tryptophan present in the pasture is metabolized in the rumen to 3-methylindole which in turn is absorbed into the bloodstream and carried to the lungs
3-methylindole causes extensive and selective necrosis of bronchiolar cells and type 1 pneumocytes and increased alveolar permeability leading to edema, thickening the alveolar interstitium and alveolar and interstitial emphysema
What are the lesions associated with ABPE?
diffuse interstitial pneumonia with severe alveolar and interstitial edema and interlobular emphysema
How do the lungs appear with ABPE?
expanded, pale and rubbery in texture
What lobes are affected with ABPE?
caudal lobes
What are the clinical signs of ABPE?
Severe respiratory distress
dyspnea
emphysema in the lungs and SQ
How do you prevent ABPE?
allow younger animals to graze the pastures first will lower the incidence in older cows by reducing the amount of Tryptophan rich grass
feeding ionophores to change the volatile fatty acid production to proprionic acid
Dictyocaulus viviparous
parasite migrates to the bronchi causing severe bronchial irritation, bronchitis, and pulmonary edema
What is the signalment for Dictyocaulus viviparous?
calves during their first summer grazing pastures that are repeated from year to year