Bone tissue/other info Flashcards

1
Q

What tissue

A

Compact bone

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2
Q

What structure

A

Osteon (Haversian system)

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3
Q

What structure

A

Central (Haversian) canal

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4
Q

What cell type

A

Osteocyte (in lacuna)

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5
Q

What structure

A

(containing cytoplasmic extensions of osteocytes) Canaliculi

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6
Q

What structure

A

(containing blood vessels and nerves)
Perforating (Volkmann’s) canal

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7
Q

What structure

A

(Containing blood vessels and nerves)
Central (Haversian) canal

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8
Q

What tissue

A

Spongy (cancellous) bone

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9
Q

Concentric rings of calcified material

A

Lamellae

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10
Q

What structure

A

Diaphysis

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11
Q

What structure

A

Epiphysis

Know both pictures

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12
Q

What Cavity

A

Medullary cavity
(filled with yellow bone marrow)

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13
Q

What tissue

A

Articular cartilage (composed of hyaline cartilage)

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14
Q

What tissue

A

Compact bone

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15
Q

What tissue

A

Spongy (cancellous) bone
(filled with red bone marrow)

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16
Q

What membrane lining bone surface

A

Periosteum

Know both pictures

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17
Q

Membrane lining cavity

A

Endosteum

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18
Q

Hematopoiesis

A

Red and white blood cell production
Produced in red bone marrow (found in spongy bone)

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19
Q

Calcium level

A

9 - 11 mg/100ml

Ca(ll) 911

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20
Q

Hypocalcemia

A

Low blood calcium levels

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21
Q

Hypercalcemia

A

High blood calcium levels

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22
Q

Organic components

A

(about 35%)
Extracellular protein fibers (mainly collagen)

Glycosaminoglycans (GAGs) and proteoglycans (protein core with GAGs attached)

Without organic components bone will shatter

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23
Q

Inorganic components

A

(about 65%)
Hydroxyapatite – crystalline pattern formed by calcium and phosphate salts (obtained from diet)

Without inorganic components bone could not hold our weight

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24
Q

Osteogenics

A

Stem cells found in periosteum and Endosteum
Able to change into osteoblasts

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25
Osteocytes
Mature bone cells - Secrete chemicals that maintain the bone extracellular matrix - Most abundant cells in the bone - Spider-shaped - Reside in lacunae
26
Osteoblasts
Bone cells that produce new bone through ossification (osteogenesis) Become osteocytes when surrounded/trapped by bone matrix
27
Osteoclasts
Large cells on internal and external bone surface Secretes acid and enzymes to break down and dissolve the bone matrix - Found in shallow depressions on bones
28
Primary bone
AKA woven bone Forms first in the womb and during repair after fractures Composed of irregularly arranged collagen fibers, maybe osteocytes, not much inorganic matrix making the bones less rigid Primary bone gets broken down by osteoclasts over time and replaced by secondary bone
29
Secondary bone
AKA Lamellar bone This is your permanent bone Contains Lamellae and regularly arranged parallel collagen fibers, making this bone much stronger than primary bone 2 types of secondary bone: - Compact - Spongy
30
What bone category
Long bone - bone is longer than it is wide (Humerus)
31
What bone category
Short bone - bone is about as long as it is wide (Trapezium / carpal bone)
32
What bone category
Irregular bone - bone's shape does not fit into other classes
33
What bone category
Flat bone -- bone is broad, flat, and thin
34
What bone category
Sesamoid bone -- round, flat bone found within tendons
35
Periosteum
Found on the outside of bones - Protects the bone - Blood vessels and nerves found in it before going into the bone - Provides attachment sites for tendons and ligaments
36
Homogenous
Of the same or a similar kind or nature "Compact bone appears homogenous"
37
Diaphysis
The central shaft (region) of long bones - Surrounds the medullary (marrow) cavity - Medularry cavity normally filled with yellow bone marrow
38
Epiphyses
The expanded portions at end of long bones - Articulate (to make a connection) with a bone at a joint - articular cartilage on the outside of the ends of the bone
39
Articular cartilage
Hyaline cartilage that helps reduce friction at joints
40
Endosteum
Membrane that lines the inner surface of the bone and the outer portion of the medullary cavity - bone cells help maintain proper bone structure in growth and remodeling
41
Intramembranous ossification
The cranium and clavicles form this way "Membrane bones" - having developed in a fibrous membrane made up of mesenchyme
42
Intramembranous ossification Step 1
Connective tissue stem cells group together at the primary ossification center and change into osteogenic cells which start to form osteoblasts
43
Intramembranous ossification Step 2
Osteoblasts make the bone matrix and become osteocytes once trapped
44
Intramembranous ossification Step 3
Primary spongy bone forms Periosteum forms
45
Intramembranous ossification Step 4
Eary compact bone forms
46
Endochondral ossification
Hyaline cartilage if replaced by bone offering in primary ossification centers These are cartilage bones which is how most bones are formed
47
Endochondral ossification step 1
Blood vessels grow and surround the hyaline cartilage Chondroblasts from the Perichondrium starts to change and form osteogenic cells which then creates the bone matrix Perichondrium turns to the periosteum
48
Endochondral ossification step 2
Osteoblasts begin to make bone matrix and surround the cartilage bone forming a ring Chondrocytes start to calcify as more bone matrix forms due blood supply being cut off
49
Endochondral ossification step 3
Osteoclasts dig holes so that blood vessels can get through the bone collar The blood brings nutrients and osteoblasts so that more bone can form inside the collar Medullary cavity starts to form
50
Endochondral ossification step 4
Osteoclasts break down most of the newly formed spongy bone to enlarge the medullary cavity Most of the ossification is complete besides growth plates (epiphyseal plate)
51
Epiphyseal plate
Hyaline cartilage between the epiphyses and diaphysis allows for growth long ways by chondrocytes dividing
52
diploe
Inner layer of spongy bone in flat bones
53
Resting zone
Aka Reserve cartilage Part of the growth plate Chondrocytes not diviting
54
Proliferation zone
Chondrocytes dividing and new cells pushed towards diaphysis Due to resistance of the solid diaphysis the epiphysis is pushed in the other direction
55
Hypertrophic zone
The older chondrocytes enlarge
56
Calcification zone
The chondrocytes die which causes them to calcify Blood vessels invade the cavities
57
Ossification zone
The calcified cartilage is replaced by bone tissue
58
Appositional growth
Growth in diameter of bones Occurs as bones grow in length
59
Vitamin A
Stimulates osteoclast activity
60
Vitamin C
Is needed in order to make collagen
61
Vitamin D
Assists with increasing absorption of calcium in digestive tract to raise the calcium levels in the body
62
Vitamin K
Increases bone desposition by stimulating activity of osteoblasts
63
Human growth hormone
AKA - HGH Produced by pituitary gland; increases general tissue growth which bone is very sensitive to
64
Thyroid hormone
AKA - Thyroxine Determines metabolic rate (of all reactions in the body)
65
Sex hormones
AKA - Estrogen, Testosterone Increases longitudinal growth and plate closure Testosterone increases appositional growth