BMSC210 CH4.3 Flashcards
What phylum do the majority of gram-negative bacteria belong to?
Proteobacteria
What are gram-negative bacteria that do not belong to the phylum Proteobacteria called?
Nonproteobacteria
What are three classes of gram-negative nonproteobacteria?
Spirochetes, CFB group, Planctomycetes
How are spirochetes characterized?
Long, spiral-shaped bodies
Why is it difficult to examine spirochetes under a conventional brightfield microscope?
They are very thin
What type of microscopy is typically used to examine spirochetes?
Darkfield fluorescent microscopy
Why are spirochetes difficult or impossible to culture?
They are highly motile
What is the axial filament of a spirochete?
Similar to a flagellum, but wraps around the cell and runs inside the cell body of a spirochete in the periplasmic space between the outer membrane and the plasma membrane.
Are there spirochetes that are human pathogens?
Yes
What are the gram-negative nonproteobacteria of the CFB group called?
Cytophaga, Fusobacterium, and Bacteroides
What are fusobacteria?
Bacteria that inhabit the human mouth - They may cause severe infectious diseases.
What type of environments are CFB bacteria adapted to?
Anaerobic environments
What is the main function of CFB bacteria in ruminant animals?
To process cellulose in the rumen
What are Cytophaga?
Motile aquatic bacteria that glide.
Which is the largest genus of the CFB group?
Bacteroides
Where are Bacteroides commonly found?
Human large intestine
What percentage do Bacteroides make up in the entire gut microbiome?
About 30%
What do bacteria like Bacteroides benefit from in the gut?
Nutrients in the gut
How do humans benefit from Bacteroides in the gut?
Prevention of pathogen colonization
What happens to the gut when populations of Bacteroides are reduced?
Increased susceptibility to pathogenic bacteria and fungi