Blood Flashcards

1
Q

_ is made of 90% water, 100+ dissolved solutes (hormones, ions, gasses); yellow and sticky

A

plasma

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2
Q

_ makes up 60% plasma protein; maintains osmotic pressure, shuttles molecules, and acts as buffer

A

albumin

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3
Q

_ are anucleate

A

erythrocytes (RBC)

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4
Q

_ are nucleate

A

leukocytes (WBC)

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5
Q

_ are cell fragments from megakaryocytes; blood clotting

A

platelets

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6
Q

_ are the indentations on both sides of disc shaped RBC; increase surface area

A

biconcave discs

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7
Q

_ (red pigment) combines with globin to make Hb

A

heme

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8
Q

_ is a protein made of 4 polypeptide chains (2 alpha, 2 beta)

A

globin

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9
Q

_ is the production of RBCs in red bone marrow

A

hematopoiesis (hemopoiesis)

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10
Q

_ are hematopoietic stem cells; all RBCs originate from

A

hemocytoblast

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11
Q

_ is the process of multipotent hematopoietic stem cells becoming committed to being RBC (functional differentiation, gene expression)

A

erythropoiesis

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12
Q

_ is the low O2-carrying capacity of blood

A

anemia

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13
Q

anemia can be caused by _ number of cells, _ hemoglobin, or _ hemoglobin

A

insufficient, decreased, abnormal

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14
Q

_ anemia is rapid blood loss

A

hemorrhagic

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15
Q

_ anemia is the rupture of RBCs

A

hemolytic

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16
Q

_ anemia is when bone marrow is impaired

A

aplastic

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17
Q

_ anemia create microcytes

A

iron deficiency

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18
Q

_ anemia from B12 deficiency

A

pernicious

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19
Q

_ from faulty globin chains

A

thalassemias

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20
Q

_ anemia is from a change in hemoglobins beta chain

A

sickle cell

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21
Q

_ from excess RBCs in bone marrow

A

polycythemia

22
Q

_ is the ability to pass through capillary walls

A

diapedesis

23
Q

_ is the protrusion of cytoplasm by forming false feet to create crawling movement

A

ameboid motion

24
Q

_ are WBC with visual granules in cytoplasm

A

granulocytes

25
_ are WBC with no visible granules in cytoplasm
agranulocytes
26
_ (most abundant) are very phagocytic and have defensins (antibiotics, destroy bacteria)
neutrophils
27
_ have digestive enzymes that defend against parasites; have role in asthma and allergies
eosinophils
28
_ (rarest) release histamines to attract other WBC to infection site
basophils
29
_ (second most common) mostly exist in tissues (rather than blood)
lymphocytes
30
_ act directly against cells with infection/tumor
T-lymphocytes
31
_ cause plasma to make antibodies
B-lymphocytes
32
_ (largest) become macrophages when leaving circulation; activate lymphocytes
monocytes
33
_ is the production of WBC; stimulated by chemical messengers in red bone marrow and mature WBC
leukopoiesis
34
_ is a low WBC count caused by cancer treatments
leukopenia
35
_ impairs normal bone marrow function by overproduction of [abnormal] WBC cloned from single cell
leukemia
36
_ leukemia = fast (from lymphoblasts)
acute
37
_ leukemia = slow (from myelocytes)
chronic
38
_ is a viral disease caused by epstein-barre virus (no cure, non-fatal)
infectious mononucleosis
39
_ are regulated by thrombopoietin
platelets
40
_ are antigens on surface of RBC (at least 30 types)
glycoprotein
41
_ are structures that bind to specific antibody/t cell receptors and can trigger immune response
antigens (agglutinogens)
42
_ is the clumping from antigen and corresponding antibody; used in blood typing
agglutination
43
_ are antibodies unresponsive to own blood type
agglutinins
44
_ occurs when fetal RBCs destroyed in immune response from blood group incompatibility between fetus and parent
erythroblastosis fetalis
45
_ is when individuals pre-donate blood for elective surgery; avoid transfusion issues or disease
autologous transfusion
46
_ is a process to control bleeding
hemostasis
47
_ is when smooth muscle contracts and causes vasoconstriction
vascular spasm
48
_ is where platelets stick to exposed collagen fibers from injury
platelet plug formation
49
_ release chemicals to make nearby platelets sticky and forms plug
platelets
50
_ is where fibrin forms a mesh (traps RBCs and platelets) to form clot
coagulation