Block2 intro to path Flashcards

1
Q

cause of disease

A

etiology

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2
Q

mechanism of disease is what?

A

pathogenesis

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3
Q

structural alteration induced in cells and tissues by the disease

A

morphologic change

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4
Q

functional consequences of the morphologic changes

A

clinical significance

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5
Q

Without or lack of formation

A

aplasia

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6
Q

a localized collection of pus in a cavity formed by the disintegration of tissue

A

abscess

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7
Q

a malignant tumor of epithelial cells arranged in glandular patterns

A

adenocarcinoma

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8
Q

a benign epithelial tumor in which the cells form glandular structures or are derived from glandular epithelium

A

adenoma

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9
Q

What is ante mortem?

What is post morten?

A

before death

after death

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10
Q

defective development or congenital absence of an organ or tissue?

A

aplasia

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11
Q

what is closed, absence of a normal opening or normally patent lumen?

A

atresia

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12
Q

what is self-dissolution; the post-mortem enzymatic degradation of cells?

A

autolysis

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13
Q

a group of neoplastic disease in which there is a transformation of normal cells into malignant cells. The cells proliferate in an abnormal way resulting in a malignant, cellular tumor

A

cancer

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14
Q

Having consistency like that of cottage cheese?

A

Caseous

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15
Q

an abnormal sac filled with gas, filled with gas, fluid, or semi-solid material that is lined by a membrane?

A

cyst

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16
Q

The causative agent in a lesion is what?

A

Etiology

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17
Q

An abnormal, tube-like passage from a hollow organ to the surface, or from one organ to another?

A

Fistula

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18
Q

What is a localized collection of extravasated blood, usually clotted?

A

Hematoma

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19
Q

What is the presence of an increased amount of blood in a part or an organ?

A

hyperemia

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20
Q

What is occurring without known cause?

A

Idiopathic

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21
Q

What is a localized area of ischemic necrosis produced by the occlusion of the blood vessels- either arterial supply or venous drainage?

A

Infarct

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22
Q

What is a local deficiency of blood due in part to functional constriction or actual mechanical obstruction of a blood vessel?

A

Ischemia

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23
Q

What is stones formation in tissue or organ?

A

Lithiasis

Colicky is a thing here

24
Q

What is the interpretation of the abnormalities in terms of severity, time, lesion, and anatomic site. For example: severe, chronic, glomerulonephritis

A

morphologic diagnosis

25
What is the morphologic changes indicative of cell death indicted by characteristic nuclear and cytoplasmic change?
necrosis
26
What is the examination of a body after death?
Necropsy
27
What is upper urinary tract stones that involve the renal pelvis and extend into at lest 2 calyces are classified as staghorn calculi?
Nephrolithiasis
28
What is a gross, pale, wedge shape, copulative necrosis?
Renal Infarct
29
What is a small projection containing fibrovascular core of connective tissue?
Papillary
30
What is a small circumscribed, solid, elevated lesion of the skin?
Papules
31
What is the sequence of events that leads to a disease or morbid process. It may be, for example, hormonal, chemical infections, genetic or traumatic in nature?
Pathogenesis
32
Neoplasia can be malignant or ______ Cancer is ______
benign malignant
33
What is inflammation of the vein?
phlebitis
34
What is an increase in the number of cells in a tissue organ, usually as a physiologic response to a stimulus?
Hyperplasia
35
This spheroidal mass protrudes upwards or outward from a normal surface. _______ may be hyperplastic, inflammatory, or neoplastic?
Polyp
36
What is a protein-rich liquid inflammation product comprised leukocytes (neutrophils), a thin fluid and cellular debris?
Pus
37
What is a prediction of the outcome of the pathological process or disease?
Prognosis
38
an infiltration of polymorphonuclear cells into an area of chronic inflammation characterized by mononuclear cells, macrophages, lymphocytes, and even plasma cells
Pyogranuloma
39
What is having a saw like edge?
Serrated
40
What is attached by a broad base?
Sessile
41
What is pus containing oftens follows a bacterial infection and liquefactive necrosis?
Suppurative
42
What is a clot of material that breaks free from primary site, is transported in the bloodstream and become lodged and adhered at a secondary site?
Thromboembolus
43
What is having a local defect or excavation of the epithelium of an organ or tissue through the basement membrane?
Ulcerated
44
What is a benign, focal malformation that resemble neoplasm in the tissue of its origin?
Harmartoma
45
What is noncancerous growths that form due to abnormal collection of blood vessels?
Hemangiomas
46
What is a mass of histologically normal tissue present at an abnormal location?
Choristoma
47
What is a type of germ cell tumor made up of a heterogeneous mixture of tissues from one or more of the germ cell layers?
Teratoma
48
Pyknosis is what?
condensation of chromatin
49
Karyorrhexis is what?
fragmentation of nuclear material
50
Karyolysis is what?
lysis of chromatin due to the action nucleases
51
Creatine Phosphokinase-MB isozyme (CPK-MB); Lactate Dehydrogenase (LDH); Troponin I and T, Myoglobin are seen in what?
heart attacks
52
What does ALT and AST that are elevated?
Hepatitis
53
What does Pancreatitis have an elevated level of?
Amylase and lipase
54
Biliary tract obstruction has what elevation?
Alkaline Phosphatase
55
What can mediate a direct attack on a target cell and initiate a self destruction cascade?
cytotoxic T cells and NK cells
56
Protein malnutrition is what disease?
Kwashiorkor
57
What is protein-calorie deficiency?
Marasmus