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Drugs list > Block 4 > Flashcards

Block 4 Flashcards

1
Q

Flucloxacillin

A

Beta lactams - Penicillins

Bactericidal – cell lysis by blocking cell wall synthesis

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2
Q

benzylpenicillin

A

Beta lactams - Penicillins

Bactericidal – cell lysis by blocking cell wall synthesis

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3
Q

amoxicillin/co-amoxiclav

A

Beta lactams - Penicillins

Bactericidal – cell lysis by blocking cell wall synthesis

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4
Q

Meropenem

A

Beta lactams - Carbapenems

Bactericidal – cell lysis by blocking cell wall synthesis

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5
Q

Ceftriaxone

A

Cephalosporins

Bactericidal – cell lysis by blocking cell wall synthesis

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6
Q

Ciprofloxacin

A

Fluoroquinolones

Bacteriostatic – inhibition of bacterial DNA coiling

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7
Q

Clindamycin

A

Lincosamides

Bacteriostatic – inhibition of bacterial protein synthesis

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8
Q

Erythromycin

A

Macrolides

Bacteriostatic – inhibition of bacterial protein synthesis

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9
Q

Metronidazole

A

Nitroimidazoles

Bacteriostatic – inhibition of bacterial DNA synthesis

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10
Q

Tetracycline

A

Tetracyclines

Bacteriostatic – inhibition of bacterial protein synthesis

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11
Q

Doxycycline

A

Tetracyclines

Bacteriostatic – inhibition of bacterial protein synthesis

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12
Q

Methotrexate

A

(DMARDs) Anti-proliferative agents (against folate activity)

Reduces lymphocyte proliferation

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13
Q

Azathioprine

A

(DMARDs) Anti-proliferative agents (against purine synthesis)

Reduces lymphocyte proliferation

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14
Q

Sulphasalazine

A

(DMARDs) Immunosupressive agents

Immunosuppressive mechanism unclear

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15
Q

Penicillamine

A

(DMARDs) Immunosupressive agents

Immunosuppressive mechanism unclear

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16
Q

Infliximab

A

(DMARDs) Biologics (monoclonal antibodies)

Bind and block proinflammatory function of TNF-alpha (infliximab)

17
Q

Rituximab

A

(DMARDs) Biologics (monoclonal antibodies)

Depletion of B cells (rituximab)

18
Q

Drugs used in the management of hypercalcaemia

A

Fluids (normal saline), furosemide (loop diuretic) - to increase renal excretion

calcitonin, alendronic acid (bisphosphonates) - Inhibition of release of calcium from bone

19
Q

Drugs used in the management of hypocalcaemia

A

IV calcium gluconate, vitamin D

Restoration of calcium levels and retention

20
Q

Drugs used in the management of vitamin D deficiency

A

Vitamin D (colecalciferol often spelt cholecalciferol), calcitriol (1,25dihydroxyvitamin D; usually only used in cases of advanced chronic kidney disease)

21
Q

Drugs used in the management of osteoporosis

A

Alendronic acid (bisphosphonates), raloxifene, (selective oestrogen receptor modulator; SERM), parathyroid hormone, denosumab (monoclonal antibody), vitamin D

Inhibition of release of calcium from bone, inhibition of osteoclast activity

Drugs list (24 decks)

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