Biology- Endocrinology Flashcards
what are hormones secreted into?
circulatory system
what do exocrine glands secrete?
substance into ducts
what kind of glands secrete hormones?
endocrine glands
what do peptide hormones bind to?
specific extracellular receptors
what does adenylate cyclase catalyze?
conversion of ATP to cAMP (cyclic adenosine monophosphate)
what does cAMP do?
relays messages from extracellular peptide hormone to cytoplasmic enzymes
what is cAMP?
cyclic AMP which is a secondary messenger
how do peptide hormones generally act?
via secondary messengers
two examples of steroid hormones?
estrogen and aldosterone
what is the common structure of steroid hormones?
ring
why can steroid hormones enter their target cells directly?
they are lipid soluble…can enter through the membrane directly.
what do steroid hormones bind to?
specific intracellular receptor proteins in cytoplasm
what happens after the steroid hormone binds?
hormone/receptor complex binds to DNA to promote the transcription of certain genes
where is the adrenal gland located?
on top of kidney
what produces ACTH?
anterior pituitary
when are corticosteroids released?
when stressed. ACTH stimulates the adrenal cortex
what secretes corticosteroids/steroid hormones?
adrenal cortex
examples of glucocorticoids?
cortisol and cortisone
what are glucocorticoids involved in?
protein metabolism and glucose regulation
what is gluconeogenesis?
making glucose from non-carbohydrates
what is the antagonist to insulin?
glucocorticoids (they raise plasma glucose)
what regulate plasma sodium and potassium levels/extracellular water volume?
mineralocorticoids
example of mineralocorticoids
aldosterone
excess aldosterone leads to what?
high blood pressure because it promotes active reabsorption of sodium and passive water reabsorption IN THE KIDNEY
where are mineralocorticoids released from?
adrenal cortex
where are androgens released from?
adrenal cortex
what are examples of catecholamines?
epinephrine and norepinephrine
where are epinephrine and norepinephrine released from?
adrenal medulla
what does epinephrine convert?
glycogen to glucose…leads to increased blood sugar and increase metabolic rate
what does epinephrine inhibit?
vegetative functions that are not necessary to immediate survival (ex: digestion)
what is aldosterone production regulated by?
reninangiotensin system