Bacterial Pathogenicity Flashcards

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1
Q

what is the life cycle of a parasite?

A

enter - attach - colonise - evade host immunity - produce harmful proteins - disseminate - release from host

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2
Q

what is a pathogen?

A

an organism capable of causing disease

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3
Q

what is a commensal?

A

an organism that is part of the normal flora

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4
Q

what is pathogenicity?

A

the ability to cause disease

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5
Q

what is virulence?

A

the ability to cause severe disease

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6
Q

what are microorganisms divided into?

A

bacteria, fungi, viruses, prions, parasites

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7
Q

what is colonisation?

A

when microbes find a new host and start to multiply

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8
Q

how is normal flora acheived?

A

getting a balance between colonised microbes and humans

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9
Q

what is an infection?

A

a disease caused by a microbe

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10
Q

what is it called when a patient’s own flora causes an infection?

A

endogenous infection

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11
Q

what is an exogenous infection?

A

if the source of microbe is flora from outside the patients body

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12
Q

what is Kochs postulates?

A

the microbe must be present in every case of the disease, the microbe must be isolated from the diseased host and grown in pure culture, the disease must be reproduced when a pure culture is introduced into a susceptible host, the microbe must be recovered from an experimentally infected host

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13
Q

what are the different ways that parasites can be transmitted?

A

person-to-person, fomites, insects, water and food

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14
Q

how are parasites transmitted via person-to-person

A

contaminated blood or other bodily fluids, touch, saliva and air

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15
Q

which part of the prokaryotic cell is used for attachment?

A

pili(fimbriae)

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16
Q

name some encapsulated infections

A

meningitis, pneumonia, otitis media and sinusitis

17
Q

name some bacteria that commonly cause encapsulated infections

A

streptococcus penumoniae, haemophilus influenzae, neisseria meningitidis and group B streptococcus

18
Q

what is the morbidity of encapsulated infections related to?

A

immune response

19
Q

what does the capsule of bacteria do?

A

mediate adhesion, immune evasion, protection from desiccation, reserves of carbohydrate, give rise to smooth colonies and capsular antigens

20
Q

where do endotoxins come from?

A

gram-negative bacteria

21
Q

where do exotoxins come from?

A

gram positive and negative bacteria