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CP Test 3 > B4-035 O2 and CO2 Transport > Flashcards

B4-035 O2 and CO2 Transport Flashcards

1
Q

CO2 diffuses [….] than O2

A

more readily

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2
Q

perfusion or diffusion limited?

gas equilibrates early along the length of the capillary

A

perfusion limited

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3
Q

perfusion or diffusion limited?

exchange can only be increased if blood flood increases

A

perfusion limited

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4
Q

perfusion or diffusion limited?

O2 (normal health), CO2, N2O

A

perfusion limited

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5
Q

perfusion or diffusion limited?

gas does not equilibriate by the time blood reaches the end of the capillary

A

diffusion limited

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6
Q

perfusion or diffusion limited?

O2 (empysema, fibrosis) CO

A

diffusion limited

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7
Q

O2 diffuses […] across the alveolar membrane

A

slowly

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8
Q

CO2 diffuses […] across the cell membrane

A

rapidly

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9
Q

dissolved oxygen contributes to the […] of oxygen in blood

A

partial pressure

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10
Q

[…] dictates hemoglobin/O2 characteristics

A

partial pressure of oxygen in blood

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11
Q

very little O2 is carried in the […]form

A

dissolved

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12
Q
  • partial pressure of O2 in blood
  • determined by molecules of O2 contained in the liquid phase
A

blood PO2

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13
Q

right shift of curve results in

A

more oxygen being unloaded where needed

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14
Q

left shift of curve indicates

A

more O2 saturation to carry oxygen where its needed

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15
Q

downward shift of curve indcates

A

change in Hemoglobin amount

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16
Q

upward shift of curve indicates

A

increase in dissolved PO2

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17
Q

a-v O2 difference reflects

A

oxygen consumption by the body

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18
Q

three forms of CO2 in blood

A

HCO3-
HbCO2
dissolved

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19
Q

as CO2 enters the blood […] leaves O2

A

hemoglobin

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20
Q

in lungs, oxygenation of Hb promotes dissociation of

A

H+

shifts equilibrium toward CO2 formation

21
Q

in lungs, oxygenation of Hb promotes H+ dissociation, CO2 is

A

released from RBCs

22
Q

causes decreased transit time through capillaries

A

exercise

23
Q

pressure gradient of […] is much higher

A

O2

24
Q

pressure gradient of […] is lower

A

CO2

10x less than O2

25
Q

a thicker capillary membrane will have a greater effect on […] diffusion

A

O2

26
Q

oxygen has a more difficult time diffusing across the membrane due to the

A

high pressure gradient

27
Q

a severe reduction in PaO2 will trigger compensatory

A

hyperventilation

28
Q

factors that effect DLO2

A
  • surface area available for diffusion
  • distance from alveolus to RBC
29
Q

an increase in the capillary membrane thickness can be detected by

A

testing the diffusing capacity of CO

30
Q

PO2 of 45mm Hg is a Hb saturation of

A

75%

31
Q

PO2 of 100 mmHg is a Hb saturation of

A

95%

32
Q

normal O2 content in blood

A

20 ml/dl

33
Q

higher than normal hemoglobin is a compensatory mechanism for

A

long term hypoxia

will still have normal O2 content, even though Hb saturation is low

34
Q

PPL at end of expiration at FRC is

A

-5 cm H2O

35
Q

a less negative PPL indicates

A

reduced elastic recoil

high compliance

36
Q

increased compliance means easy to

A

inflate

less elastic recoil

37
Q

hypoxia causes pulmonary arterial

A

vasocontriction

38
Q

increasing arterial blood PO2 only affects

A

dissolved O2, minimal change in graph

39
Q

arterio-venous O2 difference is affected by

A

O2 consumption in the tissues

40
Q

a decreased in PCO2 would signal

A

hyperventilation

41
Q

breathing 100% O2 causes a several fold increase in

A

PaO2

42
Q

if cardiac ouput and O2 consumption remain unchanged, the arterio-venous O2 difference

A

remains unchanged

43
Q

Fick Principle

A

VO2=Q x (CaO2-CvO2)

44
Q

how would anemia alter the PO2 and the total O2 content?

A

PO2 remains normal
Total O2 content is low

Hb is well oxygenated, just not enough Hb

45
Q

will mild/moderate anemia increase ventilation?

A

no, PO2 is normal so chemoreceptors do not fire

46
Q

if lung function is normal, the difference between alveolar and arterial PO2 is

A

5-10 mmHg

47
Q

O2 carrying capacity is determined by

2

A
  1. Hb concentration
  2. O2 affinity
48
Q

PCO2 at normal alveolar ventilation

A

40 mmHg

49
Q

PCO2 of >40 mmHg indicates

A

hypoventilation

CP Test 3 (17 decks)

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