B11 - Hormonal Coordination Flashcards
How the body is controlled by chemicals called hormones .
The Endocrine system .
What is the endocrine system ?
-It contains a number of GLANDS , These glands secrete hormones directly into the BLOOD STREAM .
-The blood carries the hormones all around thebody .
-But ech hormone acts on specific traget organs where it produces an EFFECT .
ONE DIFFERENCE BETWEEN THE NERVOUS SYSTEM AND THE ENDOCRINE SYSTEM ?
-The nervous system uses electrical impusles which travel down neurones .
-Wheres the endocrine system uses hormones which are chemicals these are carried in the blood stream .
ANOTHER DIFFERENCE BETWEEN THE NERVOUS SYSTEM AND THE ENDOCRINE SYSTEM ?
-Whereas signalling in the nervous system is extremely fast .
-The endocrine tends to produce a much slower effect , which is also longer lasting .
ONE KEY GLAND IN THE ENDOCRINE SYSTEM - THE PANCREAS
-Releases hormones involved in controlling the concentration of glucose in the blood .
ANOTHER KEY GLAND IN THE ENDOCRINE SYSTEM - OVARIES AND TESTES
-Release hormones involved in puberty and in reproduction .
THIRD KEY GLAND IN THE ENDOCRINE SYSTEM - THE THYROID GLAND
-Produces hormones invovled in growth and regulating the body’s basal metabolic rate (how rapidly the bodies reactions take place ,)
FOURTH KEY GLAND IN THE ENDOCRINE SYSTEM - THE ADRENAL GLANDS
They release the hormone adrenline which is produced in times of fear or stress.
Final KEY GLAND IN THE ENDOCRINE SYSTEM - THE PITUITARY GLAND .
-Located in the BRAIN .
-It is extremely important , scientist ca;; the pituitary gland a MASTER GLAND as the pituitary gland releases a number of diferent hormones into hte blood depending on the conditions .
KEY POINT ABOUT PITUITAYR GLANDS .
-The pituitary hormones act on other glands causing other homes oto be released .
-By acting on other glands , the pituitary hormones can trigger a range of different effects in the body .
What is glucose needed for ?
-Glucose is needed by eveyr cells to release energy for respiration .
-So it is very important that the concentration of glucose is kept constant as possible . THIS IS PART OF HOMEOSTASIS .
WHAT HAPPENS WHEN YOU EAT A CARBOHHYDRATE RICH MEAL AND YOUR BLOOD GLCUOSE GOES UP .
-Blood glucose concentration is monitored by the pancres .
-After a meal rich in carbohydrates , the concnetraiton of glucose in the blood can rise.
-This is sensed by Tthe PANCREAS . the pancreas then produces the hromone INSULIN .
WHAT HAPPENS WHEN YOU EAT A CARBOHHYDRATE RICH MEAL AND YOUR BLOOD GLCUOSE GOES UP . Stage two
-Insulin travels in the bloodstream all around the body and it triggers the body cells to take up the glucose from the blood .
WHAT HAPPENS WHEN YOU EAT A CARBOHHYDRATE RICH MEAL AND YOUR BLOOD GLCUOSE GOES UP . STAGE THREE
Insulin also triggers liver and muscles cells to store excess glucose as a stroage moelcule called glycogen .
WHAT HAPPENS WHEN YOU EAT A CARBOHHYDRATE RICH MEAL AND YOUR BLOOD GLCUOSE GOES UP . Stage four
-As glucose is being taken out of the blood +stored the concentration of glusoe in the blood returns to is normal level . AKA HOMESTASIS HAS TKAEN PLACE .
In some people , their blood glucose control does not work effectively .
These people have diabetes .
WHAT HAPPENS IN TYPE 1 DIABETES
The pancreas doe snot produce enough insulin .
WHAT HAPPENS IN TYPE 1 DIABETES
The pancreas does not produce enough insulin .
What does the graph show ?
-Graph shows blood glucose in a person with type 1 , diabetes as a person who does not have diabetes .
-At the start of the experiment , both people ate a meal containing the same amount of carbohydrate .
What does star one show
-In both cases , the concentration of glucose in the blood rises .
-In ther person WITHOUT DIABETES , the blood glucose concenrations rapidly returns to its normal level . Due to the effect to Insulin .
Star one (2)
-However , with a perosn with type 1a high level .
* diabetes . the blood glucsoe conentrations rises and then stays at a high level .
-That is because the pancreas cannot produce a sufficent amount of insulin .
How do people with type 1 diabetes treat their condition
-They monitortheir blood glucose concentration and inject themselves with insulin if the blood glucose rises too much example after A CARB HIGH MEAL .
WHat does star two on the graph show ?
-When the person with type 1 diabetes injects themseles with insulin , you can see that thier lood glucose concentration can fall .
Type 2 diabetes
-The body cells stop responding tto insulin produced by the pancreas .
-Again in these patients , blood glucose leevsl rise too ghigh .
How is type 2 diabetes treated
-It is often treated with a diet contraining a controlled level of carbohdyrates .
-THis is to preven blood glcuose levels from rising too high .
-People with type two diabetes are also advised to take exercise
MAJOR RISK FACTOR FOR TYPE TWO DIABETES .
-OBESITY .
-As obesity levels are increasing in the Uk , we are seeing more type 2 diabetes int he U .
WHAT HAPPENS IF THE BOOD GLUCOSE CONCENTRATION FALLS .
-If it is too low , then the pancreas releases the hormone GLUCAGON , into the bloodstream
What does glucagon do ?
-Glucagon triggers liver cells to convert glycogen stores back to glucose . This glucose is then released back into the blood .
-This causes the blood glucose concentration to return to normal .
Check the grpah , what does it show ?
-A persons blood glcuose concentration . T
-this persond oes not have diabates .
-Blood glucose concenration rises slightly and falls slightly over the course of the day . AS YOU CAN SEE .
-That is because blood glucose concentrations is controlled by a balance between insulina nd glucagon .
What does star one of the triple graph show ?
-If the glucose concentration is rises , the pancreas releases insulin ,a nd this cuases the glucose conentration to fall .
bhWhat does stat two show of the triple graph ?
-However , when the glucose concentrationf alls to certain level , the pancreas releases glcuagon . Causing the glucose conentration to rise again . y
What is a negaitve feedback cycle
-Becuase INSULIN and glucagon can have opposite effects on the blood glucose concentration . SO scientits say that they form a NEGATIVE FEEDBACK CYCLE .
Where are the adrenal glands locted ,a nd what are there effect ?
-The adrenal glands are located at the top of the kidneys .
-During times of fer and stress , the adrenal glands produce the hormone adrenaline . aDRENALINE IS RELEASED into the blood .
What is the EFFECT of adrenaline ?
-O ne of the main effects of adrenaline is to increse HEARTRATE . As he heart is beating faster , more oxygen and glucose are delievered into the body to the brain and muscles .
-Both oxygen and glucose are needed for aerobic respiation . This prepares the body to either fighrt or runaway . Scientists call this FIGHT OR FLIGHT .
Where is the thyroid glands located ?
Thyroid glands are located in the back of the neck and this releases the hormone THYROXINE .
One effect of THYROXINE
-Firstly , thyroixine stimulates the body’s basal metabolism .
(Metabolism is the sum of all the chemical reactions in the body 0
-AKA , thyroxine makes the body;s chemical reactions take place at a FASTER RATE ./
Second effect of THYROXINE
-Thyroixien plays an important role in GROWTH + DEVELOPMENT .
-the level of thyroxine in the blood is controlled by NEGATIVE FEEDBACK .
EXAM NOTE - dont need to know any specifc negative feedbac cycles even THYROXINE , but hsould have a general idea .
…
Thyroxine negative feedback cycle p1
-Level of thyroxine in the blood is monitored by the brain .
-When thyroxine lvels fall , the pituitary gland releases the hormone TSH into the bloodstream .
Thyroxine negative feedback cycle p2
-TSH triggers the thyroid glands to release mroe thyroxine into the blood .
-The increasing level of thyroxine is now detected by the brain .
-This now prevents the pituitary gland from releasinng tsh .
-The TSH levels falls . The thyroid glands release less thryoixine .
A genereal understanding ont hyroxine negative feedback cycle
-If the level of thyroxine falls , events are triggered causing the levels of thyroxine to increase .
-If it gets too high ,e veents are triggered to bring it back down .
-THIS IS A NEGATIVE FEEDBACK CYCLE .
Other negtiave feedback systems ;
-Blood glucose
-Menustral cycle
What is a really important role of the endocrine hrome ?
-In the human reproductive sytem .
-During puberty , reproductive hormones cause SECONDARY SEXUAL CHARCATERSTICS TO DEVELOP , e.g ppubic hair .
IN MEN THE TESTES
-Produce the hormone testosterone .
-Tesosterone stimulates the testes to produce sperm .
IN WOMAN , THE OVARIES
produce the hormone oestrogen .
-Once puberty begins , eggs in the ovaries stsart to mature .
-Eevery 28 days an egg is rleased this is called OVULATION .
-The reelase of an egg eveyr 28 days is part of the menustual cycle . .
S1 - what happens during the menustral cycle ?
-Before we look at the hormones invovled , every 28 days , ovlation takes place (the ovaryies relese an egg ) .
S2 what happens during the menustral cyle ?
-In prepartion for this , the utereus lining becomes thick and spogy .
s3 what happens during the menustral cyle ?
-The egg now makes its way down the uterus .
S4 what happens during the menustral cyle ?
-iF THE SPERM IS PRESENT , THE EGG CAN BE FERTILISED.
-If this happens it can implant the uterus all and develop into a baby .
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S5 what happens during the menustral cyle ?
-However , if the g does not get fertilised then btoh the gga nd the ueterus lining are released . We call this a PERIOD .
Four key homrones in the menustral Cycle (1)
-Follicle stimulaitng hormones (FSH) - CASES THE EGG TO MATURE IN THE OVARIES .
Four key hormones in the menustral cycle (2)
Lutenisng hormone (LH) causes this egg to be released in other words OVULATION .
what happens during the menustral cyle ? (3)
Oestrogen (produced by the ovary 0) and progesterone is invovled in maintaning the uterus lining , incase the egg is fertilised and implants .
How the hormones of the menustral cycle interact (1)
-In the first tsage (FSH) is released by the pituitary gland . FSH travels into the blood to the OVARIES ,w here it causes an egg to marture .
How the hormones of the menustral cycle interact (2)
-FSH travels in the blood to the ovaries where it causes an eggt o mature .
How the hormones of the menustral cycle interact (3)
-At the same time , FSH triggerds the ovaries to make oestrogen .
How the hormones of the menustral cycle interact (4)
Oestrogen causes the lining of the uterus to become thick .
How the hormones of the menustral cycle interact (5)
-Oestrogen also stops the pitruitary gland from releasing any more FSH .
How the hormones of the menustral cycle interact (6)
-Instead , the pitruiary gland now releases (LH) , LH CAUSES OVULATION .
-oNCE THE OVARY HAS RELEASED THE EGG THE OVARY PRODUCES THE HROMONE PROGESTERONE WHICH HAS two effects .
What is one effect of progesterone ;
-It stops the pituitary gland from releasing FSH and LH , tht is to prevent any more eggs from maturing or being released .
What is another effect of progesterone ;
-Progesterone keeps the lining of the uterus thick incase a fertilised egg implants .
-If fertilition DOES NOT take place , then the levels of progesteerone FALLS .
How the hormones of the menustral cycle interact (7)
-The uterus lining and the egg are now released and the woman has a period .
In the exam , we could be asked to interpet graphs of these hormones during the menustral cycle .
check sheet .
What does star one show ?
-The level of FSH rises , and this triggers the ovaries to release oestrogen .
What does star two show ?
-As the levels of the oestrogen increas e, this inhibits the production of FSH , SO THE LEVELS OF FSH FALLS .
wHAT DOES STAR three show ?
wHAT DOES STAR FOUR SHOW ?
-Lh triggers ovulation , and once thishappens , the ovaryes release porgesterone . So the progestorone levels now rise .