Autonomic Nervous System Flashcards
Which CN neurons transmit viscerosensory information?
9 and 10
What are the 2 types of viscerosensory receptors?
- Nociceptors
2. Physiologic
What type of stimuli do nociceptors respond to?
stimuli that have the potential to damage tissue or to stimuli resulting from the presence of damaged tissue.
Why is visceral pain often described as diffuse and difficult to localize?
Because receptor density is low and receptive fields are correspondingly large.
What type of stimuli do physiologic receptors respond to?
innocuous stimuli monitoring the functions of visceral structures on a continuing basis. (help to maintain homeostasis)
What are the two pathways in the viscerosensory and visceromotor systems?
- Sympathetic
2. Parasympathetic
In the viscerosensory system, what type of information does the sympathetic nervous system convey?
Information originating from nociceptors
In the viscerosensory system, what type of information does the parasympathetic nervous system convey?
Information originating from physiologic receptors
Where do viscerosensory fibers originate from?
structures that receive GVE input from the same spinal level as the one it is entering.
What type of visceral activity that enters the spinal cord reach the level of consciousness?
only information related to pain
What are the target areas of the viscerosensory system?
- Reticular Formation
2. Nucleus of Solitary Tract
What is the reticular formation made up of?
Diffuse and ill-defined collection of nuclei interspersed among all the more compact and named structures of the brainstem.
Where does the reticular formation project to?
Hyothalamus and thalamus, ultimately projects to broad areas of cortex (mostly frontal lobe).
What type of information reaches the reticular formation?
Sympathetic and Parasympathetic viscerosensory information.
What is the job of the reticulothalamic/thalamocortical pathway?
To “alert” or “activate” the cerebral cortex as a whole and constitute one important part of the ascending reticular activating system.
Where is the Nucleus of the Solitary Tract located?
Medulla
What type of information does the Nucleus of the Solitary Tract receive?
Parasympathetic viscerosensory information
Where does information from the Nucleus of the Solitary tract project to?
Several brainstem nuclei that are involved in pharyngeal and laryngeal reflexes and the central regulation of respiratory, cardiovascular, and GI fxns.
What is referred pain?
Where noxious stimuli originate in a visceral structure and are perceived as pain arising from a somatic structure. Mechanism is thought to involve a convergence of somatic and visceral information onto pools of dorsal horn neurons
What are the target tissues of the Visceromotor system?
- Cardiac Muscle (SA node)
- Smooth Muscle (blood vessels and hollow viscera)
- Glandular Epithelium (skin, hollow, and solid viscera)
What type of influence do the sympathetic and parasympathetic divisions have on target tissues?
Overlapping and anatagonist influences on target tissues located in body cavities and some structure of the head.
What does the sympathetic division of the visceromotor system innervate?
Target tissues of body wall and extremities, adrenal medulla, and most arterial blood vessels.
What are the 2 neurons involved in the pathway from Brainstem/Spinal Cord–> Target Tissues?
- Preganglionic Neuron
2. Postganglionic Neuron
Where is the cell body and axon of the preganglionic neuron?
Cell Body- CNS
Myelinated axon projects to an autonomic ganglion
Where is the cell body and axon of the postganglionic neuron?
Cell Body- Autonomic ganglion
Unmyelinated axon projects to target tissue
Where do the preganglionic neurons in the sympathetic division of visceromotor system synapse?
On chromaffin cells of adrenal medulla
Describe the synapse with target tissues of the terminal branches of postganglionic neurons.
- Postganglionic neurons have swellings containing neurotransmitter vesicles along their length, giving them a beaded appearance.
- Neurotransmitter released acts on effector cells up to 100mm away. Therefore exerting a diffuse control over target tissues.
What are the functions of the visceromotor system?
- Control of visceral functions- regulation of cardiovascular, respiratory, digestive, urinary, and reproductive organs.
- Adaptive responses to stimuli- light, temperature, stress.
Where does the sympathetic outflow in the visceromotor system originate?
Thoracolumbar area- T1-L2 (Intermediolatearl Cell Column of Lateral Horn)
How is the pathway of the sympathetic division different from parasympathetic in visceromotor system?
Generally have short preganglionic fibers and long post ganglionic fibers.
Where are the cell bodies and axons of the preganglionic neurons in the sympathetic division of the visceromotor system?
Cell bodies: Interomedial cell column of the lateral horn of T1-L2.
Axons: exit through ventral roots and enter sympathetic trunk via white communicating rami
Where are the 3 places the preganglionic neuron in the sympathetic division of the visceromotor system can synapse?
- In a paravertebral ganglion either at the same or different level.
- Pass through a paravertebral ganglion to form a splanchnic nerve
- Pass through a paravertebral ganglion to synapse directly on a chromaffin cell of adrenal medulla.
What is the adrenal medulla?
An endocrine gland that secretes both epinephrine and norepinephrine into circulation
How are the cell bodies of the postganglionic neurons in the sympathetic division of the visceromotor system grouped?
Grouped into discrete ganglia that are located at some distance from the target tissue.
- Cell bodies in paravertebral ganglion
- Cell bodies in prevertebral ganglion.
When the cell bodies are in the paravertebral ganglion, what are the 2 pathways of the axons.
Axon exits through gray communicating ramus (spinal nerve)–>target tissues of head, body wall, and extremities.
Axon exits as carotid, cardiac, or pulmonary nerve–> target tissues of head and thorax.