Aulner Nutrition And Metabloism Flashcards
Cells want to use what to make ATP
Glucose
Once glucose enters the cell, cell can now do something with the glucose and can run it through the 3 chemical reactions:
1) glycolysis
2) Krebs (citric acid) cycle
3) Electron transport chain
(happens in cytoplasm of cell), breaking glucose in half into 2 pyruvates (3 carbon chains) when doing this 1 glucose enters, some energy is released and makes +2 ATPS (through substrate level phosphorylation)→ 2 NADH molecules and 2 pyruvates.
Glycolysis
Glycolysis makes how many ATPs, NADH and pyruvate
2- ATPS
2NADH
2 pyruvate
(pyruvate into Acetyl CoA) happens after glycolysis- 2 Pyruvate go into it and lose a couple carbons.
The conversion step
Coming out of Conversion step
+2 NADH, +2 CO2 (carbon dioxides) & 2 Acetyl
CoA (that will enter the Krebs cycle
What happens to the 2 pyruvates?
-Oxygen present= the 2 pyruvates will go into mitochondria (starting Krebs cycle)
-No oxygen present= convert pyruvate to lactates or lactic acid
What doesn’t enter the Krebs cycle and what does enter the Krebs cycle
Pyruvate’s don’t enter krebs
Acetyl CoA enter Krebs cycle
Conversion of pyruvate into acetyl CoA) NOT a part of Krebs Cycle
Happens before Krebs cycle after glycolysis
- (happen in mitochondria), 2 Acetyl CoA enter Krebs cycle goes around releasing (+2 ATPs, +2 FADH2, +6NADH, 4 CO2)
Krebs (citric acid) cycle
happen in mitochondria)
• High electron (e-) brought in with NADH and FADH2, can pass from protein to protein inside mitochondria. H+ brought in from NADH and FADH2 are pumped using energy from e- through protein into mitochondria. The e- at the end get tired and go to 02 (final electron acceptor).
Electron transport chain
What is the final electron acceptor
Oxygen
What does NADH AND FADH2 bring in to mitochondria
High electrons and H+ (hydrogen ions)
Why do we pump the hydrogens (H+) from one side of membrane to the other?
to let them come back through ATP synthase (protein), every time H+ come back you make a new ATP (total +32 ATPS and +H20 made by oxidative phosphorylation
**Starting with one glucose→ able to produce how many ATPs using aerobic respiration.
+36 ATPs
Can we use lipids to generate ATP?
Sure, we can, change fatty acids into Acetyl Coa and can stick them into Krebs cycle (no glycolysis at all).
• PROBLEM= this creates ketones (acidic) as waste = ketoacidosis
Can we use amino acids to generate ATPS?
Some amino acids can convert into Acetyl CoA, put that in Krebs cycle
• Problem can get ketones (acidic) and can be dangerous, and Nitrogen waste.
Can we use amino acids or fatty acids to create glucose?
• Yes, it’s not easy, it uses lots of energy (liver). Would have to change a fatty acid into a carbohydrate and an amino acid into carbohydrate. It’s called:
Gluconeogenesis=making glucose from a non-carbohydrate molecule