Atracurio Flashcards

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1
Q

Que es el atracurio ?

A

Un relajante neuromuscular NO despolarizante, del grupo Benzilisoquinolona

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2
Q

Inicio de accion del Atracurio

A

Intermedio: 2-4min

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3
Q

Duracion del Atracurio

A

Intermedia: 30-40min

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4
Q

Eliminacion del Atracurio

A

Por hidrolisis de Hoffman (80%)

20% Biliar

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5
Q

Metabolito de Atracurio, es activo o inactivo?

A

Leudanocina, inactivo.

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6
Q

Que puede producir el metabolito del Atracurio?

A

En Re-dosis, la Leudanocina puede producir depresion cardiovascular y excitacion del SNC. (Efecto acumulativo)

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7
Q

Potencia del Atracurio

A
  • Superior –> Vecuronio

- Inferior –> Cisatracurio

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8
Q

Efectos secundarios del Atracurio

A

Por liberacion de histamina:

  • broncoespasmo
  • Hipotension
  • vasodilatacion periferica
  • Rash cutaneo
  • Taquicardia
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9
Q

Dosis inicial (de intubacion) del Atracurio

A

0.5 mg/kg

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10
Q

Redosis del Atracurio

A

0.1-0.2 mg/kg

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11
Q

ED 95 del Atracurio

A

0.1-0.2 mg/kg

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