arthritis (needs reviewal) Flashcards
JIA/JRA (childhood arthritis)
juvenile idiopathic arthritis
3 major subtypes
Systemic, oligoarticular, polyarticular
all JIA symptoms include
joint pain, swelling, and inactivity stiffness
last at least 6 weeks
younger than 16
systemic JIA etiology + epidemiology
idiopathic, autoimmune
least common
systemic JIA presentation
fever - high spiking, intermittent fever
rash - salmon pink, axilla/around waist. worse with heat
arthritis - wrists, knee, ankles but also any joints
systemic - hepatospenomegaly, lymphandenopathy, serositis. uveitis is rare
systemic JIA diagnosis
fever must be present for 2 weeks, arthritis for 6 weeks
systemic JIA labs
leukocytosis, thrombocytosis, anemia, ESR and CRP elevation
ANA and RF always negative
systemic JIA treatment
NSAIDs, oral glucocorticoids, DMARDS (nonbiologic or biologic), peds rheum referral
DMARDS
suppress bodys overactive immune system
take weeks to months to become effective
systemic JIA complications
destructive damage
macrophage activation syndrome
severe growth retardation
oligoarticular JIA etiology + epidemiology
idiopathic, autoimmune
most common, F>M
oligoarticular JIA presentaiton
arthritis - usually asymmetrical, large joints (knees, ankles, wrists, elbows)
limping w/o pain that improves throughout day
oligoarticular JIA diagnosis
less than 5 joints during first 6 months
oligoarticular JIA labs
ANA - might be positive
ESR - normal/mildly elevated
oligoarticular JIA treatment
NSAIDs, glucocorticoids
regular eye exams
oligoarticular JIA complications
uveitis - 20%
leg length discrepancy
polyarticular JIA etiology + epidemiology
idiopathic, autoimmune
bimodal distribution (2-5, and 10-14)
polyarticular JIA presentation
arthritis - symmetric
<10 years - 1-2 joints, epreads rapidly
older children - rapid onset in multiple joints