AP03 - Histology of the digestive tract and togopraphy of the small and large intestines Flashcards

1
Q

What defines the bounderies of he small intestine?

A

pylorus

ileocaecal-junction

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2
Q

What are the 3 main sections to the intestine?

A

duodenum
jejunum
ileum

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3
Q

What is the general function of the large intestine?

A

delaying passage of liquid to allow more time for absorption

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4
Q

In embryological development of the GIT, what help relocate the gut on its’ return to the abdominal cavity?
Where are they?

A

retention bands

duodenal-jejunal flexure
splenic flexure

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5
Q

Whch parts of the intestine are fused to the posterior abdominal wall?

A

ascending and decening colon

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6
Q

What are the 5 main phases in the GIT functino?

A
ingestion
fragmentation
digestion
absorption
elimination
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7
Q

What are the layers to the GIT?

A

Mucosa
Submucosa
muscularis propria
serosa or adventitia

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8
Q

What are the sub layers to the mucosa?

A

epithelium
lamina propria
muscularis mucosa

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9
Q

What are the sub layers to the muscularis propria?

A

circular muscle
auerbach’s myenteric plexus
longitudinal muscle

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10
Q

What is the function of the lamina propria?

A

has blood and lymph vasculature

supports the epithelium, which is avascular

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11
Q

What is the structure of hte lip?

A

Vermillion zone is keratinized stratified squamous epithelia

underneath is thick in sensory bits and capillaries, making it pink

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12
Q

Where and what is contained within the circumvalate papillae?

A

8-12 just before tongue terminal sulcus

salivary von Ebner glands hae entry into surrounding grooves

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13
Q

What is the structure of taste buds?

A

gustatory cells and gustatory microvilli connect the taste pore to the underlying sensory nerve

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14
Q

What does the pulp cavity of a tooth contain?

what is another name for it?

A

capillaries and sensory fibres

perioduntium

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15
Q

What is the main chemical constituent of enamel, and whihc cell type forms this?

A

calcium hydroxypatite, formed in the developing tooth by ameloblasts

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16
Q

What type of epithelium lines the oesophagus?

What protects it?

A

nonkerainized stratified squamous epithelium

oesophageal gland secretions

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17
Q

What do mucous neck cells secrete?

A

mucous

bicarbonate

18
Q

What do parietal cells secrete?

A
gastric acid (HCl)
intrinsic factor (Calcium absorption)
19
Q

What do enterchromaffin like cells secrete?

20
Q

What do chief cellls secrete?

A

pepsin

gastric lipase

21
Q

What do D cells secrete?

A

somatostatin

22
Q

What do G cells secrete?

23
Q

What are enteroendocrine cells?

A

umbrel term for cells of the GIT and pancreas with endocrine function (doesn’t secrete steroids)

24
Q

by what factor do villi and microvilli increase surface area by?

A

villi x3
microvilli x10
(combined x30)

25
Where are the crypts of Leiberkuhn and what do they produce?
colon THEY ARE GLANDS lining of the crypts contain stem cells, which differentiate and migrate out, forming goblet cells, enterocytes, and enteroendocrine cells
26
What types of cells are in crypts of Leiberkuhn?
Paneth cells - producing defensin | Stem cells
27
What are Peye's patches?
lymphatic tissue found throughout the ileum | help immunity, monitoring intestinal bacterial populations
28
How might you differentiate between ileum and duodenum?
ileum - peyer's patches in mucosa | duodenum - bicarbonate secreting mucous cells
29
How does lymph in the bowel differ from those draining other tissues?
Lacteals absorbs fats, transporting chyle into Lymph vessels
30
What is the difference between stenosis and atresia?
both are congenital narrowing of spaces atresia is full, stenosis is partial
31
What are taenia coli?
three ribbons of longitudinal muscle, following the ascending, transverse, and descending colons respectively
32
What is a merkel's diverticulum?
congenital bulge in the lower ileum | 2-3% of the population
33
Why might a colonoscopy in women be harder?
their colon is a bit longer
34
What 2 GI structures do we consider when describing defecation?
sigmoid colon | rectum
35
Where are the internal and external anal sphincter located? What lies between them?
right at the end of the rectum anal sinuses
36
Where are the sensory nerves stimulating defecation? | What is theme of this nerve?
sigmoid colon | pelvic nerve
37
What type of nerve stimulates the involuntary defecation reflex, and where are the muscles is stimulates?
autonomic parasympathetic | sigmoid colon and internal anal sphincter
38
What nerve controls the external anal sphincter, what kind of control is this?
pudendal nerve somatic control
39
What is caeliac disease?
AI attack on cells when gliadin from gluten is absorbed
40
What is McBurney's point?
point over the abdomen 1/3 of distance from ASIS to umbilicus marks the attachment of appendix to the colon