Aortic Dissection Flashcards

1
Q

Aortic dissection is rare

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe the pathophysiology of aortic dissection

A

tear in the tunica intima of the wall of the aorta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which syndromes are associated with aortic dissection?

A

Turner’s and Noonan’s syndrome

collagens: Marfan’s syndrome, Ehlers-Danlos syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which infection is associated with aortic dissection?

A

syphilis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the most important risk factor re aortic dissection?

A

Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Can pregnancy be associated with aortic dissection

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which valve deformity is associated with aortic dissection

A

bicuspid aortic valve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe the characterstic chest pain associated with aortic dissection?

A

typically severe, radiates through to the back and ‘tearing’ in nature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What will the pulse be like in aortic dissection?

A

weak or absent carotid, brachial, or femoral pulse

variation (>20 mmHg) in systolic blood pressure between the arms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which murmur would you hear in aortic dissection?

A

aortic regurgitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe how symptoms would manifest if the coronary arteries were involved

A

angina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe how symptoms would manifest if the spinal arteries were involved

A

paraplegia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe how symptoms would manifest if the distal aorta was involved

A

limb ischaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What ECG changes would you see in aortic dissection

A

the majority of patients have no or non-specific ECG changes.
In a minority of patients, ST-segment elevation may be seen in the inferior leads

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What two classifications are used for aortic dissection?

A

Stanford classification

DeBakey classification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe the Stanford classification Type A & Type B

A

type A - ascending aorta, 2/3 of cases

type B - descending aorta, distal to left subclavian origin, 1/3 of cases

17
Q

Describe the Debakey Classification

A

type I - originates in ascending aorta, propagates to at least the aortic arch and possibly beyond it distally
type II - originates in and is confined to the ascending aorta
type III - originates in descending aorta, rarely extends proximally but will extend distally

18
Q

What is the investigation of choice for aortic dissection?

A

CT angiography of the chest, abdomen and pelvis

19
Q

Is CT angiography better for stable or unstable patients?

A

suitable for stable patients and for planning surgery

20
Q

What will you see on CT angiography?

A

a false lumen is a key finding in diagnosing aortic dissection

21
Q

What would you see on CXR?

A

widened mediastinum

22
Q

Transoesophageal echocardiography (TOE) is suitable for which patients?

A

more suitable for unstable patients who are too risky to take to CT scanner

It’s important to remember that patients may present acutely and be clinically unstable.

23
Q

What classification determines management?

A

Stanford classification Type A & Type B

24
Q

How do you manage a Type A dissection?

A

surgical management,

but blood pressure should be controlled to a target systolic of 100-120 mmHg whilst awaiting intervention

25
Q

How do you manage a Type B dissection?

A

conservative management
bed rest
reduce blood pressure IV labetalol to prevent progression

26
Q

Complications of backward tear?

A

aortic incompetence/regurgitation

MI: inferior pattern is often seen due to right coronary involvement

27
Q

Complications of a forward tear?

A

unequal arm pulses and BP
stroke
renal failure

28
Q

Why might focal neurological defects present with aoritc dissection?

A

propagation of the intimal tear to branch arteries

due to mass effects as the expanding aorta compresses surrounding structures

29
Q

compression of the sympathetic trunk by the expanding aortic dissection would result in what?

A

Horner’s syndrome (classically ptosis, miosis and anhidrosis)

30
Q

A 52-year-old male presents with tearing central chest pain. On examination he has an aortic regurgitation murmur. An ECG shows ST elevation in leads II, III and aVF. What is the diagnosis?

A

ascending aorta dissection
AR murmur raises suspicion of inferior myocardian infarction AND proximal aortic dissection

Other features may include pericardial effusion, carotid dissection and absent subclavian pulse.

31
Q

What groups is aortic dissection most common in?

A

Afro-carribean males aged 50-70 years.

32
Q

Describe the pathophysiology of aortic dissection

A

This occurs when there is a flap or filling defect within the aortic intima. Blood tracks into the medial layer and splits the tissues with the subsequent creation of a false lumen.

33
Q

Where anatomically is aortic dissection more common?

A

most commonly occurs in the ascending aorta or just distal to the left subclavian artery (less common)