Antiulcer Drugs

Question 1

Omeprazole

Answer 1

CNS: dizziness, headache
GI: Abdominal pain, constipation, diarrhea
Musculoskeletal: back pain
Respiratory: cough, URI
Skin: rash

Question 2

Sucralfate (Carafate)

Answer 2

Prevent gastric mucosal injury from drug-induced ulcers
-GI: Constipation
CNS: Dizziness, headache 
GI: nausea, flatulence, dry mouth
Skin: Rash, pruritus

Question 3

Misoprostol (Cytotec)

Answer 3

Prevent and treat peptic ulcer

• CNS: Headache
• GI: Abdominal pain, D/N/V, constipation, flatulence.
• Menstrual disorders, miscarriage.

-Black box warning: Prevent use of drug during pregnancy. Drug can cause abortion.

Question 4

Aluminum hydroxide (Amphojel)

Answer 4

Peptic ulcer
Hyperacidity
Reflux esophagitis

-GI: Anorexia, constipation, GI obstruction
Metabolic: hypophosphatemia.
Musculoskeletal: Osteomalacia