Antiemetics

Question 1

Promethazine hydrochloride

Answer 1

CNS: drowsiness, sedation, confusion.

• Dry mouth, blurred vision.
• Hypotension, hypertension.
• Urine retention.
• Photosensitivity, rash

Question 2

Ondansetron hydrochloride (Zofran)

Answer 2

Nausea

-Selective serotonin (5-HT3) receptor antagonists

• CNS: dizziness, fatigue, headache, malaise, sedation, fever
• CV: arrhythmias, chest pain
• GI: constipation, diarrhea
• GU: Gynecologic disorder, urine retention.
• Respiratory: hypoxia
• Skin: pruritus, rash
• Chills, injection-sit reaction