Antiseizure Medications

Question 1

_________ is involved in the coordination of impulses and responses.

Answer 1

Dopamine

Question 2

Gamma-aminobutyric inhibits nerve activity and is important in preventing
overexcitability or stimulation such as ________ activity.

Answer 2

seizure

Question 3

____________ important in arousal and sleep and in preventing depression and promoting
motivation

Answer 3

serotonin

Question 4

The drug class ________, are used to treat seizures by decreasing excitability and hyper-excitability. Some examples of this drug class include __________ + _______________.

Answer 4

Hydantoins;

Phenytoin (Dilantin) + Fosphenytoin

Question 5

What are the 4 major side effects to monitor for with antiseizure meds. like henytoin or Dilantin?

Answer 5

-steven Johnson syndrome
-gingival hyperplasia
-liver toxicity
-bone marrow suppression

Question 6

Barbiturates and barbiturate like drugs decrease excitability and hyperexcitability. What are 2 drugs that belong to this class?

Answer 6

-phenobarbital
-primidone

Question 7

what are the general side effects of most antiepileptic or sedative drugs?

IE. hydantoins, barbiturates, benzodiazepines,

Answer 7

-CNS depression
-lethargy
-fatigue
-constipation
-dry mouth
-drowsiness
-anorexia
-arrythmias
-changes in BP

Question 8

true or false?
Barbiturates can lead to physical dependence and cause withdrawal symptoms.

Answer 8

true

Question 9

What are 2 side effects of Phenobarbital + Primidone related to the bladder and sexual function that may occur?

Answer 9

urinary retention and decreased libido

Question 10

Phenobarbital, Primidone (barbiturates) can decrease the effects of _________, which will make it less effective in preventing blood clots?

Answer 10

warfarin

Question 11

true or false?
If you drink alcohol while on a barbiturate or benzodiazepine, you could cause a further depression of the CNS.

Answer 11

true

Question 12

______________ causes muscle relaxation and relieve anxiety without substantially affecting cortical function.

Answer 12

benzodiazepines

Question 13

Clobazam, clonazepam, diazepam belong to what drug class?

Answer 13

benzodiazepines

Question 14

benzodiazepines are highly addictive, they should never be stopped abruptly? So how should they be stopped?

Answer 14

these drugs need to be tapered

Question 15

What side effect should you monitor for while a patient is taking a benzodiazepine, related to the bladder?

Answer 15

urinary retention

Question 16

Ethosuximide + methsuximide are examples of which drug class?

Answer 16

succinimides

Question 17

succinimides treat _______ seizures.

Answer 17

absent

Question 18

Drugs that modulate GABA - which means excitability is reduced and overactivity is prevented, are used to treat:

Answer 18

-prevent migraines
-absent seizures
-manic episodes

Question 19

-Diamox
-Divalproex
-Valproic acid
-Zonisamide

belong to which drug class?

Answer 19

GABA inhibitors

Question 20

hyperammonemia
thrombocytopenia and pancreatitis are 3 adverse effects associated with which drug class?

Answer 20

GABA inhibitors

Question 21

true or false?
Carbamazepine is used to treat generalized or focal seizures.

Answer 21

true

Question 22

Lamotrigine modulates excitatory neurotransmitters to treat ________.

Answer 22

seizures

Question 23

Levetiracetam is another drug used to treat seizures or _________.

Answer 23

epilepsy

Question 24

Topiramate is a drug used to treat seizure’s associated with what syndrome?

hint: chef gusteau is my mate

Answer 24

(LGS) Lennox gastaut syndrome.

Question 25

What disease is characterized by lack of coordination, tremors, rigidity and weakness of muscles?

Answer 25

Parkinson's disease or parkinsonism

Question 26

true or false? bradykinesia develops due to trouble maintaining posture or position and difficulty performing intentional movements, while also moving extremely slow and sluggish.

Answer 26

true

Question 27

carbidopa/levodopa is a dopaminergic drug used to treat what kind of disease that affects movement due to some kind of damage or issue to basal ganglia?

Answer 27

Parkinson's Disease

Question 28

you need to monitor patients ________ status who are on dopaminergic drugs because of the risk of HTN + prolonged QT intervals.

Answer 28

cardiac

Question 29

if a dopaminergic is taken with an MOAI, there is an increased risk of an ________ ________.

Answer 29

hypertensive crisis

Question 29

____________ are used to treat Parkinson's due to it helping restore balance in the basal ganglia. Some examples of drugs in this drug class include: benztropine, diphenhydramine trihexyphenidyl

Answer 29

anticholinergics

Question 30

Carbidopa/Levodopa is taken as a combination drug because one facilitates the ___________ of the other.

Answer 30

absorption