Antianginal Drugs Flashcards
What is angina pectoris
when the supply of oxygen and nutrients in the blood is insufficient to meet the demands of the heart, the heart muscle “aches”
What is ischemia
poor blood supply to an organ
What is ischemic heart disease
poor blood supply to the heart
What is a myocardial infarction (MI)
necrosis, or death of the cardiac tissue
What is stable angina triggered by?
physical or mental exertion, that will resolve with rest or nitrates
What is unstable angina?
new onset or worsening angina that is unpredictable, and rest/meds do not resolve
What may acute coronary syndrome lead to?
MI, can result from unstable angina
When does vasospastic angina occur?
occurs spontaneously often at rest, it is common at night and early morning, more common in women/smokers, nitrates/calcium channel blockers will treat it
When is microvascular angina due to?
due to coronary microvascular dysfunction or spasms, can occur with exertion or at rest, may respond less to nitrates
What drug classes are used to treat angina?
-nitrates or nitrites
-beta blockers
-calcium channel blockers
What are nitrates/nitrites drug names
-nitroglycerin (rapid/long acting)
-isosorbide dinitrate (rapid/long acting)
-isosorbide mononitrate (long acting)
What is atenolol used for in angina treatment?
prophylactic (to prevent) angina pectoris
What is diltiazem used to treat?
(calcium channel blocker)
-treats A-fib/flutter
-paroxysmal supraventricular tachycardia
What can beta blockers cause?
-hypo and hyperglycemia
-weight gain if heart failure is developing
-decreased pulse rate
