Antenatal Tests II: Maternal Fluid & Tissue

Question 1

Outline the tests that are routinely ordered during the first antenatal visit (and why)

Answer 1

• Ferritin, omega 3, FBC, Urine MCS (check for deficiencies/conditions in mother)
• Blood group (test to see if Anti-D Prophylaxis is required)
• Rubella, Hep B/C, syphilis, HIV (screen for infection)

Question 2

Aisde from routine tests, what other tests may be ordered at a first antenatal consult?

Answer 2

• Chlamydia
• Thalassaemia
• Vitamin D
• Early OGTT (why?)
• Pap smear

Question 3

What genetic conditions do we screen for during pregnancy

Answer 3

• Spina bifida
• Trisomies (13, 18, 21)

Question 4

When do we do combined first trimester screening?

Answer 4

from 9wks to less than 14 wks

Question 5

What happens in the setting of low PAPP-A on CFTS? What do we do about it?

Answer 5

• Low PAPP-A is associated with significant increase in risk of baby being small for gestational age
• We do extra uterine doppler during morphology scan, and sometimes do additional growth surveilance