Amino Acids Flashcards
What is an amino acid in acidic conditions?
R
H3N+—C—-COOH
H
What is an amino acid in alkaline conditions?
R
H3N+—C—-COO-
H
What is an amino acid in pH=7
R
H3N+—C—-COO-
H
Zwitterion
What are proteins?
Monomers are amino acids
Condensation reaction links
peptide linke= amide link
What are the other structures of proteins?
1˚- chain of amino acids
2˚- a helix B pleated sheet
3˚- Disulphide bridge, hydrophobic interactions, ionic
Amino Acids can be analysed by….
Thin layer chromatography
must be highlighted by UV on ninydrin
What are enzymes?
Proteins
Biological catalysts with stereospecific active sites
Drugs act as inhibitors by occupying active site
DNA
AT 2
CG 3
Must be able to draw the bonds
Anticancer drugs
Transplatin- no affect
Cisplatin- binds to guanine and prevents DNA replication but occurs also in healthy cells