adrenergic pharmacology Flashcards

1
Q

all adrenergic receptors are what kind of receptors

A

g protein coupled receptors

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2
Q

what type of g protein coupled receptor is alpha1

A

g q increases calcium concentration increases contraction

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3
Q

what type of g protein coupled receptor is alpha 2

A

gi inhibitory deceases camp

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4
Q

what type of g protein coupled receptor is beta 1 2 3

A

stimulatory increases camp gs

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5
Q

what effects do alpha 1 adrenoceptors cause

A

vasoconstriction
increased peripheral resistance
(blood flow)
increased blood pressure
increased closure of bladder spincters
mydriasis- dilation of pupil

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6
Q

what effects do alpha 2 adrenoceptors cause

A

inhibits noreadrenaline
inhibits acetylcholine release
inhibits insulin release

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7
Q

what effects do beta 1 adrenoceptors cause

A

increased heart rate
increased lipolysis
increased myocardial contractility
increased renin

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8
Q

what effects do beta 2 adrenoceptors cause

A

vasodilation
decreased peripheral resistance
bronchodilation
increased glycogenolysis
increased glucagon release
relaxes uterine smooth muscle

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9
Q

are alpha 1 adrenoceptors more sensitive to nore adrenaline or adrenaline

A

nore adrenaline

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10
Q

are alpha 2 receptors more sensitive to nore adrenaline or adrenaline

A

adrenaline

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11
Q

are beta 1 receptors more sensitive to adrenaline or nore adrenaline

A

equally sensitive to both

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12
Q

are beta 2 receptors more sensitive to adrenaline or nore adrenaline

A

can be equal or more sensitive to adrenaline

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13
Q
A
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